Caspase-8: Products

Caspases are a family of cytosolic aspartate-specific cysteine proteases involved in the initiation and execution of apoptosis. They are expressed as latent zymogens and are activated by an autoproteolytic mechanism or by processing by other proteases (frequently other caspases). Human caspases can be subdivided into three functional groups: cytokine activation (caspase-1, -4, -5, and -13), apoptosis initiation (caspase-2, -8, -9, -and -10), and apoptosis execution (caspase-3, -6, and -7).

Caspases are regulated by a variety of stimili, including APAF1, CFLAR/FLIP, NOL3/ARC, and members of the inhibitor of apoptosis (IAP) family such as BIRC1/NAIP, BIRC2/cIAP-1, BIRC3/cIAP-2, BIRC4/XIAP, BIRC5/Survivin, and BIRC7/Livin. IAP activity is modulated by DIABLO/SMAC or PRSS25/HTRA2/Omi. Cell-permeable and irreversible peptide inhibitors are also available for different caspases.

Showing 1-10 out of 10 Caspase-8 Products

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Caspase-8 Inhibitor Z-IETD-FMK

FMK00732  
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Caspase-8 Colorimetric Assay Kit

BF410014  
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Caspase-8 Fluorometric Assay Kit

BF210014  
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Human/Mouse Caspase-8 Antibody

SW, WBAF16504  
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Human/Mouse Caspase-8 Antibody

WBAF7053  
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Human Caspase-8 Antibody

WBMAB7043  
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Recombinant Human Caspase-8 Protein

 705-C82  
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Recombinant Human Caspase-8 Protein, CF

 705-C8/CF2  
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Human Caspase-8 Antibody

ICC/IFMAB8135 
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Proteome Profiler Human Ubiquitin Array


Contains 4 membranes-each spotted in duplicate with 49 different antibodies to ubiquitin target proteins
ARY027 
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