Caspase-8: Products

Caspase-8, also known as MCH5, FLICA and MACH alpha 1, is a 28 kDa member of the peptidase C14A family of enzymes. It is widely expressed and is considered an initiating caspase for the apoptotic cascade. Caspase-8 acts on a wide variety of substrates including Pro-Caspases-3, -4, -6, -7, -9 and -10, c-FLIPL and Pro-Caspase‑8 itself. Caspase-8 is recruited to the death-inducing signaling complex (DISC) that forms around the death domains of the oligomerized receptors. Multiple rounds of cleavage generate Caspase-8 p10 and p18 which heterodimerize and then associate into the active tetrameric enzyme containing two p10 and two p18 subunits.

 

Showing 1-10 out of 10 Caspase-8 Products

page of 1
Results Per Page
DescriptionApplicationCat#CitationsImages 

Caspase-8 Inhibitor Z-IETD-FMK

FMK00760  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Caspase-8 Colorimetric Assay Kit

K113-10027  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Caspase-8 Fluorometric Assay Kit

K112-10017  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Human/Mouse Caspase-8 Antibody

KO, WBAF7055  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Human/Mouse Caspase-8 Antibody

SW, WBAF16507  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Human Caspase-8 Antibody

WBMAB7043  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Recombinant Human Caspase-8 Protein

Enzyme Activity705-C82  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Recombinant Human Caspase-8 Protein, CF

Enzyme Activity705-C8/CF2  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Human Caspase-8 Antibody

ICC/IFMAB8135 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Proteome Profiler Human Ubiquitin Array


Contains 4 membranes-each spotted in duplicate with 49 different antibodies to ubiquitin target proteins
ARY0271  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....
page of 1
Results Per Page