Chordin-like 2/CHRDL2: Products

Chordin-like 2 (CHL2, CHRDL2, or BNF-1), is a secreted glycoprotein that functions as a BMP antagonist. It is expressed in chondrocytes in developing joint cartilage, osteoblasts, myotubes, brain, some carcinomas, and the genitourinary system (e.g. uterus, prostate, testis, bladder). CHL2 binds to multiple TGF-beta superfamily proteins including BMP-2, -4, -5, -6, -7, GDF-5, Activin A, and TSG. It prevents the binding of BMPs to type 1 and type 2 receptors as well as BMP-induced cellular responses. CHL2 reduces the rate of matrix deposition by mesenchymal cells, acting as a negative regulator of cartilage formation.

Showing 1-10 out of 10 Chordin-like 2/CHRDL2 Products

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Mouse Chordin-like 2/CHRDL2 Antibody

IHC, IP, WBMAB2520 
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Human Chordin-like 2/CHRDL2 Antibody

IHC, WBAF2448 
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Human Chordin-like 2/CHRDL2 Biotinylated Antibody

IHC, WBBAF2448 
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Mouse Chordin-like 2/CHRDL2 Antibody

WBAF2520 
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Human Chordin-like 2/CHRDL2 Antibody

Flow, WBMAB24481 
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Mouse Chordin-like 2/CHRDL2 Biotinylated Antibody

WBBAF2520 
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Human Chordin-like 2/CHRDL2 Antibody

IP, WBMAB2448 
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Recombinant Human Chordin-Like 2, CF

 9127-CH 
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Recombinant Mouse Chordin-Like 2 Protein, CF

 2520-CH/CF 
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Recombinant Mouse Chordin-Like 2 Protein

 2520-CH 
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