Common beta Chain: Products

The high-affinity receptors for Interleukin-3 (IL-3), IL-5, and Granulocyte-Macrophage Colony-stimulating Factor (GM-CSF) consist of a cytokine-specific a chain, and a shared common beta chain subunit (CD131) that is essential for receptor signaling. CD131 also associates with the receptor for Erythropoietin, forming a tissue-protective heteroreceptor complex. Phosphorylation of CD131 following receptor activation imparts growth and survival signals to the responding hematopoietic cells.

Showing 1-7 out of 7 Common beta Chain Products

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Human Common  beta  Chain Antibody

Flow, WBAF9062  
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Human Common  beta  Chain APC-conjugated Antibody

FlowFAB906A1  
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Human Common  beta  Chain Biotinylated Antibody

WBBAF9061  
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Human Common  beta  Chain PE-conjugated Antibody

FlowFAB906P 
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Human Common  beta  Chain Antibody

WBMAB906 
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Recombinant Human Common beta Chain Fc Chimera Protein, CF

 906-CB 
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Human Common beta Chain (NP_000386) VersaClone cDNA

RDC1170 
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