Filter Results
clear

By Category

By Common Name

clear

By Citation

clear

By Brand

Compounds for Embryonic Stem Cell Research: Products

For many stem cell experiments, especially those with therapeutic applications, it is important to culture embryonic stem (ES) cells under defined conditions in order to reduce experimental variability. The addition of small molecules to ES cell culture media can aid in the optimization of ES cell survival, proliferation, and maintenance of pluripotency. Under certain conditions, the use of bioactive small molecules may serve as a substitute for undefined culture media. The undifferentiated and pluripotent state of ES cells can be enhanced by activation of the Wnt signaling pathway and by the addition of indole derivatives, such as ID 8. In addition, Tocris biochemicals and compounds can be used to induce the differentiation of ES cells into specialized cell types. For example, alkyl hydrazone derivatives, such as IDE-1, can activate TGF-beta signaling and induce the differentiation of ES cells into definitive endoderm.

Showing 1-29 out of 29 Compounds for Embryonic Stem Cell Research Products

page of 1
Results Per Page
DescriptionApplicationCat#CitationsImages 

Y-27632 dihydrochloride


Selective p160ROCK inhibitor
1254107  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

IWP 2


PORCN inhibitor; inhibits Wnt processing and secretion
353312  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

XAV 939


Potent tankyrase inhibitor
374815  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

LY 294002 hydrochloride


Prototypical PI 3-kinase inhibitor; also inhibits other kinases
113059  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

SB 216763


Potent, selective GSK-3 inhibitor
161650  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

PD 98059


MEK inhibitor
121356  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

endo-IWR 1


Wnt/beta-catenin signaling inhibitor; axin stabilizer
35324  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Cyclopamine


Inhibitor of Hedgehog (Hh) signaling
16235  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Sodium butyrate


Histone deacetylase inhibitor
3850 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

BIO


Potent, selective GSK-3 inhibitor
319410  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Tranylcypromine hydrochloride


Irreversible inhibitor of LSD1; also inhibits MAO
38523  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

IWP 4


Potent inhibitor of Wnt/beta-catenin signaling
5214 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

IDE 1


Induces definitive endoderm formation in mouse and human ESCs
40152  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

CKI 7 dihydrochloride


CK1 inhibitor
5329 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Pluripotin


Dual ERK1/RasGAP inhibitor. Maintains ESC self-renewal
4433 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

KY 02111


Inhibits canonical Wnt signaling. Promotes differentiation of human ESCs and iPSCs into cardiomyocytes
4731 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Sinomenine hydrochloride


Anti-inflammatory; causes mast cell degranulation and histamine release
3848 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

QS 11


ARFGAP1 inhibitor; modulates Wnt/beta-catenin signaling
33241  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Theanine


Glutamate receptor ligand
3847 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

IDE 2


Induces definitive endoderm formation in mouse and human ESCs
4016 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

A 939572


Potent SCD-1 inhibitor
4845 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

PluriSln 1


SCD-1 inhibitor
4847 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

ID 8


Sustains self-renewal and pluripotency of ESCs
3853 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Cardiogenol C hydrochloride


Induces cardiomyocyte differentiation in ESCs
3851 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Gatifloxacin


Antibiotic; inhibits bacterial type II topoisomerase
3849 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

SR 3677 dihydrochloride


Potent, selective Rho-kinase (ROCK) inhibitor
36671  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Cardionogen 1


Inhibitor of Wnt/beta-catenin signaling
4475 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Stauprimide


Inhibits NME2 nuclear translocation; primes ESCs for differentiation
3741 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

HLM 006474


E2F transcription factor inhibitor
5283 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....
page of 1
Results Per Page