Filter Results
clear

By Category

By Common Name

clear

By Citation

clear

By Brand

Compounds for Mesenchymal Stem Cell Research: Products

Mesenchymal stem cells (MSCs) are self-renewing cells characterized by their fibroblast-like appearance and their ability to differentiate into adipocytes, chondrocytes, and osteoblasts. MSCs can be isolated from bone marrow and several other tissues. The isolated cells, often referred to as mesenchymal stromal cells, contain a heterogeneous population of cells, including a subset that demonstrate stem cell properties. MSCs can be maintained and differentiated through the use of growth factors, recombinant proteins, and small molecules. Small molecules, used alone or in combination with recombinant proteins, can facilitate mechanistic studies, enhance MSC expansion, and induce differentiation. For example, Pioglitazone, Troglitazone, or the combination of IBMX and Dexamethasone facilitate adipogenesis while Kartogenin enhances chondrogenesis. When used for mechanistic studies, small molecules can be used to rapidly activate or inhibit signaling pathways of interest. Tocris Bioscience offers a broad selection of highly pure small molecules that can be used to enhance MSC growth and differentiation as well as to facilitate mechanistic studies of MSC differentiation.

Showing 1-19 out of 19 Compounds for Mesenchymal Stem Cell Research Products

page of 1
Results Per Page
DescriptionApplicationCat#CitationsImages 

Forskolin


Adenylyl cyclase activator
109962
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Phorbol 12-myristate 13-acetate


Protein kinase C activator
120123
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Retinoic acid


Endogenous retinoic acid receptor agonist
06954
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

H 89 dihydrochloride


Protein kinase A inhibitor
291030
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Dexamethasone


Anti-inflammatory glucocorticoid
11263
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

L-Ascorbic acid


Enhances the generation of iPSCs; increases reprogramming efficiency
40554
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

SB 216763


Potent, selective GSK-3 inhibitor
161672
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Indomethacin


Cyclooxygenase inhibitor (COX-1 > COX-2)
17086
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Pioglitazone hydrochloride


Selective PPARγ agonist; antidiabetic agent
41244
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

5-Azacytidine


DNA methyltransferase inhibitor
38424
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Sodium butyrate


Histone deacetylase inhibitor
3850
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Troglitazone


Selective PPARγ agonist; antidiabetic agent
31143
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

TCS 2210


Inducer of neuronal differentiation in MSCs
38771
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Kartogenin


Potently induces chondrogenesis in MSCs
4513
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Strontium chloride


Calcium sensing receptor (CaSR) agonist
4749
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Zebularine


DNA methyltransferase and cytidine deaminase inhibitor
22933
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

EC 23


Synthetic retinoid; induces differentiation of stem cells
4011
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

CW 008


PKA signaling activator; promotes osteogenesis from hMSCs
5495
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

2-Phospho-L-ascorbic acid trisodium salt


Ascorbic acid derivative; maintains differentiation potential in bone marrow-derived MSCs
5778
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....
page of 1
Results Per Page