Filter Results
clear

By Category

By Common Name

clear

By Citation

clear

By Brand

Compounds for Stem Cell Differentiation: Products

Stem cells have the ability to differentiate into specialized cell subtypes depending upon their level of potency. For instance, embryonic and induced pluripotent stem cells can give rise to cells of all three germ layers: ectoderm, mesoderm, and endoderm. Adult stem cells are generally considered to have limited potency and differentiate into a restricted number of cell types. In order to generate populations of specialized cell types for regenerative medicine, drug screening, or disease and development models, researchers must control and direct the differentiation of stem cells. Cell fate decisions can be directed by natural or chemically synthesized small molecules. For instance, a specific inhibitor of glycogen synthase kinase-3 beta can induce neuronal differentiation in pluripotent stem cells. Combinations of specific cytokines and sodium butyrate, a histone deacetylase inhibitor, have been shown to direct the differentiation of stem cells into hepatocytes. Tocris provides a complete range of bioactive small molecules to control the differentiation of stem cells into defined derivatives.

Showing 1-50 out of 61 Compounds for Stem Cell Differentiation Products

page of 2
Results Per Page
DescriptionApplicationCat#CitationsImages 

Forskolin


Adenylyl cyclase activator
109955
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

DMSO, sterile filtered


Solvent
317610
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

DAPT


γ-secretase inhibitor
263434
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

IBMX


PDE inhibitor (non-selective)
284510
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Dorsomorphin dihydrochloride


Potent AMPK inhibitor
309343
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Metformin hydrochloride


Activator of LKB1/AMPK; antidiabetic agent
28649
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

DMH-1


Selective ALK2 inhibitor
41268
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Retinoic acid


Endogenous retinoic acid receptor agonist
06954
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Dexamethasone


Anti-inflammatory glucocorticoid
11263
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

AICAR


AMPK activator
284014
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

1-Oleoyl lysophosphatidic acid sodium salt


Endogenous agonist of LPA1 and LPA2
38541
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Fluoxetine hydrochloride


5-HT reuptake inhibitor
09277
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Purmorphamine


Smo receptor agonist
45511
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

SP 600125


Selective JNK inhibitor
149691
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

AMD 3100 octahydrochloride


Highly selective CXCR4 antagonist
329913
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

LDN 193189 dihydrochloride


Potent and selective ALK2 and ALK3 inhibitor; promotes neural induction of hPSCs
60532
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

A 769662


Potent AMPK activator
333618
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

IWP 4


Potent inhibitor of Wnt/β-catenin signaling
5214
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

SIS3


Selective Smad3 inhibitor; inhibits TGF-βR1 signaling
52912
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Lin28 1632


RNA binding protein Lin28 inhibitor; promotes mESC differentiation; also bromodomain inhibitor
6068
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

PD 173074


FGFR1 and -3 inhibitor
304417
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

5-Azacytidine


DNA methyltransferase inhibitor
38424
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Sodium butyrate


Histone deacetylase inhibitor
3850
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

IDE 1


Induces definitive endoderm formation in mouse and human ESCs
40152
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

ISX 9


Neurogenic agent; induces neuronal differentiation of SVZ progenitors and also induces cardiomyogenic differentiation
44391
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Zebularine


DNA methyltransferase and cytidine deaminase inhibitor
22933
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Thioridazine hydrochloride


Dopamine receptor antagonist; antipsychotic
30701
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

IDE 2


Induces definitive endoderm formation in mouse and human ESCs
4016
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Kartogenin


Potently induces chondrogenesis in MSCs
4513
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

A 939572


Potent SCD-1 inhibitor
4845
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

SW 033291


High affinity 15-PGDH inhibitor; promotes hematopoiesis and hepatocyte proliferation
5759
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

KY 02111


Inhibits canonical Wnt signaling. Promotes differentiation of human ESCs and iPSCs into cardiomyocytes
4731
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Strontium chloride


Calcium sensing receptor (CaSR) agonist
4749
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Neurodazine


Induces neurogenesis in mature skeletal muscle cells
3656
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Stauprimide


Inhibits NME2 nuclear translocation; primes ESCs for differentiation
3741
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

TWS 119


GSK-3β inhibitor; induces neuronal differentiation in ESCs
3835
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Cardiogenol C hydrochloride


Induces cardiomyocyte differentiation in ESCs
3851
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

TCS 2210


Inducer of neuronal differentiation in MSCs
38771
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

EC 23


Synthetic retinoid; induces differentiation of stem cells
4011
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Cardionogen 1


Inhibitor of Wnt/β-catenin signaling
4475
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

PluriSln 1


SCD-1 inhibitor
4847
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

KHS 101 hydrochloride


Selective inducer of neuronal differentiation in hippocampal neural progenitors
4888
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

GSA 10


Smo receptor agonist
4918
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Shz 1


Activator of early cardiac genes in pluripotent stem cells; induces differentiation in M-PBMCs
4923
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

ITD 1


Selective inhibitor of TGF-β signaling; induces cardiomyocyte differentiation in ESCs
50681
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Neuropathiazol


Selective inducer of neuronal differentiation in hippocampal neural progenitors
5186
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

CCG 1423


Induces intermediate mesoderm differentiation from ESCs; Rho/SRF pathway inhibitor
5233
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

FH 1


Enhances iPSC-derived hepatocyte differentiation and maturation
5254
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

CKI 7 dihydrochloride


CK1 inhibitor
5329
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

CW 008


PKA signaling activator; promotes osteogenesis from hMSCs
5495
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....
page of 2
Results Per Page