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Connexin 46/GJA3: Products

GJA3 (Connexin 46) is a component of lens fiber gap junctions. Congenital cataract is the leading cause of visual disability in children. Defects in GJA3 are a cause of zonular pulverulent cataract type 3. Both normal hypoxic tissue (lens) and adaptive hypoxic tissue (breast tumor) utilize GJA3 as a protective strategy from hypoxia. GJA3 may provide a new direction for drug development for breast cancer treatment.

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Human Connexin 46/GJA3 (AAD42925) VersaClone cDNA

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