Cyclooxygenase Inhibitors: Products

Cyclooxygenase (COX), also known as prostaglandin G/H synthase, is a membrane bound enzyme partly responsible for the catalysis of prostanoid synthesis. COX is expressed as at least three different isoforms. COX-1 is constitutively expressed and thought to regulate a number of 'housekeeping' functions such as vascular hemostasis, renal blood flow, and glomerular function. COX-2 expression is tightly regulated and induced by inflammatory mediators such as growth factors, cytokines, and endotoxin. COX-3 appears to be much more strictly regulated spatially and is observed in greatest abundance in cerebral cortex.

Showing 1-26 out of 26 Cyclooxygenase Inhibitors Products

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Resveratrol


Cyclooxygenase inhibitor
14187
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Acetaminophen


Cyclooxygenase inhibitor; may be selective for COX-3
17063
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Indomethacin


Cyclooxygenase inhibitor (COX-1 > COX-2)
17086
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Celecoxib


Selective cyclooxygenase-2 (COX-2) inhibitor
3786
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Aspirin


Cyclooxygenase inhibitor; NSAID
40922
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NS 398


Cyclooxygenase-2 (COX-2) inhibitor
094213
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Piroxicam


Cyclooxygenase-1 (COX-1) inhibitor
0960
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Naproxen sodium


Cyclooxygenase inhibitor
2655
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Niflumic acid


Cyclooxygenase-2 (COX-2) inhibitor; GPR35 agonist
41122
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Diclofenac sodium salt


Cyclooxygenase inhibitor; NSAID
4454
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Flufenamic acid


Calcium-activated chloride channel blocker; NSAID. Also activates TRPC6
45221
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DuP 697


Cyclooxygenase-2 (COX-2) inhibitor
14305
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SC 560


Cyclooxygenase-1 (COX-1) inhibitor
15501
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Flurbiprofen


Cyclooxygenase inhibitor
1769
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Nimesulide


Cyclooxygenase-2 (COX-2) inhibitor
24703
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Talniflumate


CaCC blocker and Cl-/HCO3- exchange inhibitor
2510
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Tenidap


NSAID, cyclooxygenase (COX-1) inhibitor. Also opener of KIR2.3
2580
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FK 3311


Cyclooxygenase-2 (COX-2) inhibitor
2776
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(S)-(+)-Ibuprofen


Cyclooxygenase inhibitor (COX-1 > COX-2)
2796
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SC 58125


Selective cyclooxygenase-2 (COX-2) inhibitor
2895
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Etodolac


Selective cyclooxygenase-2 (COX-2) inhibitor; NSAID
3871
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SC 236


Selective cyclooxygenase-2 (COX-2) inhibitor
3919
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Valdecoxib


Selective and potent COX-2 inhibitor
4206
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NCX 4040


NO-donating aspirin; anti-inflammatory and antitumor
4531
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NCX 466


Cyclooxygenase-inhibiting nitric oxide donor
4537
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FR 122047 hydrochloride


Cyclooxygenase (COX-1) inhibitor
15077
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