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Cyr61/CCN1: Products

Cyr61, also known as IGFBP-10 and CCN1, is a 50 kDa matricellular glycoprotein that regulates the growth and adhesion of vascular endothelial cells, fibroblasts, and monocytes. Cyr61 induces VEGF upregulation, angiogenesis, and tumorigenesis through interactions with integrins alpha V beta 3, alpha V beta 5, alpha M beta 2, and alpha 6 beta 1. Cyr61 is cleaved by plasmin within its VWF domain which generates an N-terminal fragment that is not associated with the matrix but retains the ability to induce endothelial cell migration.

Showing 1-3 out of 3 Cyr61/CCN1 Products

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Human Cyr61/CCN1 Quantikine ELISA Kit

ELISADCYR101  
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Human Cyr61/CCN1 DuoSet ELISA

ELISADY4055 
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Quantikine Immunoassay Control Set 786 for Human Cyr61/CCN1


For use with catalog number DCYR10
CtrlQC73 
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