Dkk-2: Products

Dickkopf related protein 2 (Dkk-2) is a member of the Dickkopf family of secreted Wnt modulators. Dkk proteins modify Wnt engagement of a receptor complex composed of a Frizzled protein and either LRP-5 or LRP-6. Kremen-1 and Kremen-2 are also high affinity receptors for Dkk-1 and Dkk-2. Depending on the cellular context, Dkk-2 can either activate or inhibit canonical Wnt signaling. Dkk proteins are expressed in mesenchymal tissues and control epithelial transformation. Dkk-2 expression is induced by Wnts in bone and is thought to enhance bone density by promoting terminal differentiation of osteoblasts and mineral deposition.

 

Showing 1-6 out of 6 Dkk-2 Products

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Recombinant Human Dkk-2 Protein

Bioactivity6628-DK2  
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Recombinant Human Dkk-2 Protein, CF

Bioactivity6628-DK/CF2  
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Mouse Dkk-2 Antibody

IHC, WBAF24352  
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Recombinant Mouse Dkk-2 Protein

Bioactivity2435-DKB 
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Recombinant Mouse Dkk-2 Protein, CF

Bioactivity2435-DKB/CF 
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Mouse Dkk-2 Biotinylated Antibody

WBBAF2435 
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