Dopamine D3 Receptor Antagonists: Products

DRD3 is the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. It is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variations may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing results in transcript variants encoding different isoforms. This variant represents the predominant transcript and encodes the longer isoform (a).

Showing 1-8 out of 8 Dopamine D3 Receptor Antagonists Products

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Eticlopride hydrochloride


Selective D2/D3 antagonist
18476
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PG 01037 dihydrochloride


D3 receptor selective antagonist
3887
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SB 277011A dihydrochloride


Selective D3 antagonist
42071
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Nafadotride


Highly potent, preferential D3 antagonist
13472
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U 99194 maleate


Potent, selective D3 antagonist
13572
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NGB 2904


Potent and selective D3 antagonist
26351
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PNU 177864 hydrochloride


Highly selective D3 antagonist
3355
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GSK 789472 hydrochloride


D3 antagonist. Also D2 partial agonist
3940
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