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EGF R/ErbB1: Products

EGF R (epidermal growth factor receptor), also known as HER-1, ErbB1, or ErbB, is a transmembrane receptor tyrosine kinase that binds a subset of the EGF family ligands including EGF, Amphiregulin, TGF-alpha, Betacellulin, Epiregulin, HB-EGF, and Epigen. Ligand binding induces EGF R homodimerization as well as heterdimerization with ErbB2, resulting in kinase activation, tyrosine phosphorylation and cell signaling. EGF R can also be recruited to form heterodimers with the ligand-activated ErbB3 or ErbB4. EGF R signaling regulates multiple biological functions including cell proliferation, differentiation, motility, and apoptosis. EGF R is overexpressed in a wide variety of tumors and is the target of several anti-cancer drugs. Soluble receptors consisting of the extracellular ligand binding domain are generated by alternate splicing in human and mouse.

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Human Phospho-EGF R/ErbB1 (Y1086) Antibody


Recombinant Monoclonal Antibody.
ICC/IF, SW, WBMAB8967 
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Mouse Magnetic Luminex Assay

LXSAMSM5  
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Recombinant Human EGF R/ErbB1 Fc Chimera Protein, CF

 344-ER5  
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Human EGF R/ErbB1 Antibody

CyTOF-ready, ELISA(Cap), Flow, ICC/IF, IHC, IP, WBAF2316  
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Human Phospho-EGF R/ErbB1 (Y1173) Antibody

CyTOF-ready, Flow, ICC/IF, IHC, SW, WBAF10955  
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Proteome Profiler Human Phospho-Kinase Array Kit


Contains 4 sets of 2 membranes - each spotted in duplicate with antibodies against 43 different kinases and 2 related total proteins
ARY003B103  
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Recombinant Human EGF R/ErbB1 Protein

 1095-ER4  
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Human Phospho-EGF R/ErbB1 DuoSet IC ELISA

ELISADYC1095B-211  
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Proteome Profiler Human Phospho-RTK Array Kit


Contains 4 membranes - each spotted in duplicate with 49 different RTK antibodies
ARY001B117  
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Mouse EGF R/ErbB1 Antibody

IHC, SW, WBAF12802  
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Human EGF R/ErbB1 Biotinylated Antibody

ELISA(Det), Flow, WBBAF2314  
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Human Phospho-EGF R/ErbB1 (Y1068) Antibody

CyTOF-ready, Flow, WBMAB35702  
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Human Phospho-EGF R/ErbB1 (Y845) Antibody

CyTOF-ready, Flow, ICC/IF, IHC, WBAF33942  
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Human Total EGF R/ErbB1 DuoSet IC ELISA

ELISADYC1854-26  
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Human EGF R/ErbB1 Antibody

WBMAB10956  
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Human EGF R/ErbB1 Quantikine ELISA Kit

ELISADEGFR02  
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Mouse Luminex Assay

LXSAMS 
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Human EGF R/ErbB1 (aa 746-750 deletion) Antibody

ICC/IF, SW, WBMAB8336 
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Human Phospho-EGF R/ErbB1 (Y1086) Antibody

ICC/IF, SW, WBMAB89671 
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Human EGF R/ErbB1 DuoSet ELISA

ELISADY2312  
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Human Phospho-EGF R/ErbB1 (Y1068) DuoSet IC ELISA

ELISADYC3570-23  
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Recombinant Mouse EGF R/ErbB1 Fc Chimera Protein, CF

 1280-ER1  
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Mouse EGF R/ErbB1 Biotinylated Antibody

IHC, WBBAF1280 
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Human EGF R/ErbB1 PE-conjugated Antibody

FlowFAB10951P1  
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Human Phospho-EGF R/ErbB1 (Y869) Antibody

ICC/IF, WBMAB8130 
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Human Phospho-EGF R/ErbB1 (Y1197) Antibody

ICC/IF, WBMAB8274 
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Human EGF R/ErbB1 Fluorescein-conjugated Antibody

FlowFAB10951F1  
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Human EGF R/ErbB1 Antibody

CyTOF-ready, FlowMAB10951 
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Human EGF R/ErbB1 (Y1197) Antibody

WBMAB8058 
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Mouse EGF R Quantikine ELISA Kit

ELISAMEGFR0 
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Phospho-EGF R/ErbB1 (Y1068) Fluorescein-conjugated Antibody

FlowIC3570F1  
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PD 158780


Potent ErbB receptor family inhibitor
2615 
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Iressa


Orally active, selective EGFR inhibitor
300011  
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Human EGF R/ErbB1 APC-conjugated Antibody

FlowFAB10951A 
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Human EGF R/ErbB1 Alexa Fluor® 488-conjugated Antibody

FlowFAB10951G 
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Human EGF R/ErbB1 Alexa Fluor® 647-conjugated Antibody

FlowFAB10951R 
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Phospho-EGF R/ErbB1 (Y1068) PE-conjugated Antibody

FlowIC3570P 
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AG 490


EGFR-kinase inhibitor. Also JAK2, JAK3 inhibitor
04148  
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Genistein


EGFR kinase inhibitor. Also estrogen and PPARγ ligand
11104  
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AG 1478 hydrochloride


Highly potent EGFR-kinase inhibitor
127613  
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BIBX 1382 dihydrochloride


Highly selective EGFR-kinase inhibitor
24161  
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Human EGF R/ErbB1 (CAA25240) VersaClone cDNA

RDC0973 
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Human EGF R/ErbB1 Alexa Fluor® 700-conjugated Antibody

FlowFAB10951N 
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Human EGF R/ErbB1 Alexa Fluor® 750-conjugated Antibody

FlowFAB10951S 
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Human EGF R/ErbB1 Alexa Fluor® 594-conjugated Antibody

FlowFAB10951T 
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Human EGF R/ErbB1 Alexa Fluor® 350-conjugated Antibody

FlowFAB10951U 
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Human EGF R/ErbB1 Alexa Fluor® 405-conjugated Antibody

FlowFAB10951V 
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