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ERK1: Products

ERK1 and ERK2 (also known as MAPK3 and MAPK1) are 44 and 42 kDa Ser/Thr kinases, respectively. They are part of the Ras-Raf-ERK signal transduction cascade often found downstream of growth factor receptor activation. ERK1 and ERK2 were initially isolated and cloned as kinases activated in response to insulin and NGF. They are expressed in most, if not all, mammalian tissues. Dual threonine and tyrosine phosphorylation activate both ERKs, at Thr202/Tyr204 for human ERK1 and Thr185/Tyr187 for human ERK2.

ERK5, also known as Big Mitogen-activated Protein Kinase 1 (BMK1) and MAPK7, is activated by several mechanisms, including receptor tyrosine kinases, G protein-coupled receptors, and osmotic stress. Like ERK1 and ERK2, ERK5 contains the conserved Thr-Glu-Tyr activation motif in its activation loop. Unlike these ERKs, however, ERK5 contains a unique C-terminal domain that regulates its activation and nuclear translocation.

Showing 1-20 out of 20 ERK1 Products

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Human/Mouse Phospho-ERK1 (ERK1 T202/Y204, ERK2 T185/Y187) Antibody


Recombinant Monoclonal Antibody.
SW, WBMAB18251 
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Human/Mouse/Rat Phospho-ERK1(T202/Y204)/ERK2 (T185/Y187) Antibody

Flow, IHC, SW, WBAF101811  
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Phospho-ERK1 (T202/Y204)/ERK2 (T185/Y187) DuoSet IC ELISA

ELISADYC1018B-216  
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Human/Mouse/Rat Phospho-ERK1 (T202/Y204)/ERK2 (T185/Y187) Antibody

Flow, ICC/IF, SW, WBMAB10186  
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Human/Mouse/Rat ERK1/ERK2 Antibody

IHC, WBMAB15765  
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Proteome Profiler Human Phospho-Kinase Array Kit


Contains 4 sets of 2 membranes - each spotted in duplicate with antibodies against 43 different kinases and 2 related total proteins
ARY003B75  
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Human/Mouse/Rat ERK1/ERK2 Antibody

SW, WBAF15764  
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Human/Mouse/Rat Phospho-ERK1 (T202/Y204) DuoSet IC ELISA

ELISADYC1825-29  
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Human/Mouse/Rat ERK1 Antibody

IHC, WBAF1575 
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Human ERK1 Antibody

IHC, WBMAB1940 
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Human Phospho-ERK1 (T202/Y204)/ERK2 (T185/Y187) Antibody

WBMAB1825 
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Human/Mouse/Rat ERK1/ERK2 Antibody

WBMAB15761 
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Proteome Profiler Human Phospho-MAPK Array Kit


Contains 4 membranes - each spotted in duplicate with 26 different MAPK antibodies
ARY002B54  
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Recombinant Human Active ERK1 Protein, CF

 1879-KS1  
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Human ERK1 Antibody

WBAF1940 
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Human ERK1 Antibody

WBAF1879 
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Pluripotin


Dual ERK1/RasGAP inhibitor. Maintains ESC self-renewal
4433 
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Human Total ERK1 DuoSet IC ELISA

ELISADYC1940-21  
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