Endothelin ETA Receptor Antagonists: Products

EDNRA and EDNRB (endothelin A and B receptors, respectively) are members of the rhodopsin-like 7-transmembrane receptor family. EDNRA binds endothelins ET-1 and ET-2 preferentially, and is expressed on vascular smooth muscle where it mediates vasoconstriction. EDNRB binds all three endothelin forms equally, and is expressed on endothelial cells where it mediates vasodilation.

Showing 1-5 out of 5 Endothelin ETA Receptor Antagonists Products

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BQ-123


Selective ETA antagonist
11883  
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FR 139317


Highly potent, selective ETA antagonist
1210 
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Sulfisoxazole


Endothelin ETA antagonist
0731 
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CI 1020


Highly selective, orally active ETA antagonist
2942 
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BMS 182874 hydrochloride


Highly selective, orally active non-peptide ETA antagonist
14412  
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