Endothelin ETB Receptor Antagonists: Products

EDNRA and EDNRB (endothelin A and B receptors, respectively) are members of the rhodopsin-like 7-transmembrane receptor family. EDNRA binds endothelins ET-1 and ET-2 preferentially, and is expressed on vascular smooth muscle where it mediates vasoconstriction. EDNRB binds all three endothelin forms equally, and is expressed on endothelial cells where it mediates vasodilation.

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BQ 788 sodium salt


Selective ETB antagonist
15005  
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IRL-1038


ETB antagonist
11951  
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IRL-2500


Potent ETB antagonist
1838 
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