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Endothelin-1: Products

Endothelin-1 (ET-1) is a vascular endothelium derived peptide that acts as a potent vasoconstrictor. It is processed by a furin-like protease to yield a peptide termed Big ET-1. Big ET-1 is then cleaved by ECE-1, producing the mature form ET-1 (1-21). ET-1 expression is induced by mechanical stimulation, various hormones, and pro-inflammatory cytokines. Its production is inhibited by nitric oxide, prostacyclin, and atrial natriuretic peptide (ANP). ET-1 exerts its vasoconstrictor effects primarily through the receptor ETA on vascular smooth muscle cells. It also acts through the ETB receptor on vascular smooth muscle and endothelial cells. ET-1 additionally stimulates cardiac myocyte proliferation and contractility, regulates secretion by hypothalamic and pituitary cells, and promotes neutrophil extravasation and activation.

Showing 1-10 out of 10 Endothelin-1 Products

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Human Magnetic Luminex Assay

LXSAHM7  
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Build your own with our Luminex Assay Customization Tool.

Endothelin-1 Quantikine ELISA Kit

ELISADET1009  
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Human Luminex Assay

LXSAH4  
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Human Endothelin-1 QuantiGlo ELISA Kit

ELISAQET00B19  
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Human Endothelin-1 C-Terminus Antibody

ELISA, ICC/IFMAB34401  
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Endothelin 1 (human, porcine)


Potent vasoconstrictor peptide
11606  
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Quantikine Immunoassay Control Set 907 for Endothelin-1


For use with catalog numbers DET100, SET100, PDET100
CtrlQC82 
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Proteome Profiler Human Angiogenesis Array Kit


Contains 4 membranes - each spotted in duplicate with 55 different cytokine antibodies
ARY00746  
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Endothelin Pan Specific DuoSet ELISA

ELISADY11601  
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QuantiGlo Immunoassay Control Set 732 Human Endothelin-1


For use with catalog number QET00B
CtrlQC197 
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