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ErbB2/Her2: Products

ErbB2, also called Neu and Her2, is a transmembrane glycoprotein in the ErbB family of tyrosine kinase receptors for EGF superfamily growth factors. ErbB2 is widely expressed in epithelial cells and over-expressed in a large number of breast carcinomas. ErbB2 has no identified ligands but heterodimerizes with ErbB1/EGF R, ErbB3, or ErbB4 to form higher affinity signaling complexes. The protease ADAM10 releases a 110 kDa soluble fragment of ErbB2 from the cell surface. ErbB2 plays roles in development, cancer, communication at the neuromuscular junction, and regulation of cell growth and differentiation. The ErbB2/ErbB3 heterodimer is expressed in the majority of breast, skin, ovary and gastrointestinal tumors and transduces a highly mitogenic signal in response to neuregulin 1 (NRG1; heuregulin 1) or NRG2. ErbB3, ErbB2 and neuregulin are all required for formation of the sympathetic nervous system.

Showing 1-44 out of 44 ErbB2/Her2 Products

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Human Magnetic Luminex Assay

LXSAHM 
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Recombinant Human ErbB2/Her2 Fc Chimera Protein, CF

 1129-ER 
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Human Luminex Assay

LXSAH 
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Human ErbB2/Her2 Antibody

B/N, Flow, IHC, WBAF1129 
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Human ErbB2/Her2 Antibody

ELISA(Cap), Flow, ICC/IF, IHC, WBMAB1129 
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Human ErbB2/Her2 PE-conjugated Antibody

FlowFAB1129P 
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Human ErbB2/Her2 Biotinylated Antibody

ELISA(Det), ICC/IF, IHC, WBBAF1129 
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Proteome Profiler Human Phospho-RTK Array Kit


Contains 4 membranes - each spotted in duplicate with 49 different RTK antibodies
ARY001B 
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Human ErbB2/Her2 Herstatin Isoform Antibody

IHCMAB11291 
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Human Phospho-ErbB2/Her2 (Y1248) Antibody

IHC, SW, WBAF1768 
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Human Phospho-ErbB2/Her2 DuoSet IC ELISA

ELISADYC1768-2 
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Human Phospho-ErbB2/Her2 (Y1196) Antibody

IHC, SW, WBAF4438 
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Human ErbB2/Her2 Quantikine ELISA Kit

ELISADHER20 
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Human Total ErbB2/Her2 DuoSet IC ELISA

ELISADYC1129-2 
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Mouse ErbB2/Her2 Antibody

IHC, WBAF5176 
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Human ErbB2/Her2 APC-conjugated Antibody

FlowFAB1129A 
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AG 490


EGFR-kinase inhibitor. Also JAK2, JAK3 inhibitor
04148  
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AG 825


Selective ErbB2 inhibitor
15554  
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PP 3


Negative control for PP 2 (Cat. No. 1407)
27944  
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Human ErbB2/Her2 Herstatin Isoform Antibody

WBMAB4360 
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Human ErbB2/Her2 Alexa Fluor® 594-conjugated Antibody

FlowFAB1129T 
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Mouse ErbB2/Her2 Antibody

FlowMAB6744 
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Mouse ErbB2/Her2 PE-conjugated Antibody

FlowFAB6744P 
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Mouse ErbB2/Her2 APC-conjugated Antibody

FlowFAB6744A 
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Human ErbB2/Her2 Alexa Fluor® 488-conjugated Antibody

FlowFAB1129G 
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Human ErbB2/Her2 Alexa Fluor® 647-conjugated Antibody

FlowFAB1129R 
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Human ErbB2/Her2 DuoSet ELISA

ELISADY1129B 
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Mouse ErbB2/Her2 Alexa Fluor® 594-conjugated Antibody

FlowFAB6744T 
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TAK 165


Potent and selective ErbB2 inhibitor
3599 
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AEE 788


Potent EGFR and VEGFR inhibitor
53181  
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BMS 599626 dihydrochloride


Potent, selective EGFR and ErbB2 inhibitor
5022 
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GW 583340 dihydrochloride


Potent dual EGFR/ErbB2 inhibitor; orally active
2239 
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HKI 357


Dual irreversible inhibitor of ErbB2 and EGFR
3580 
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AV 412


Potent inhibitor of EGFR, ErbB2 and Abl receptor tyrosine kinases
4397 
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CP 724714


Potent and selective ErbB2 inhibitor
5973 
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Mouse ErbB2/Her2 (NP_001003817) VersaClone cDNA

RDC1103 
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Human ErbB2/Her2 (NP_004439) VersaClone cDNA

RDC1022 
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Rat ErbB2/Her2 (AAH61863) VersaClone cDNA

RDC0475 
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Human ErbB2/Her2 (NP_001005862) VersaClone cDNA

RDC1023 
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Quantikine Immunoassay Control Set 826 for Human ErbB2/Her2


For use with catalog number DHER20
CtrlQC86 
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Proteome Profiler Mouse Phospho-RTK Array Kit


Contains 4 membranes - each spotted in duplicate with 39 different RTK antibodies
ARY014 
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Proteome Profiler Human sReceptor Array, Non-hematopoietic


Contains 4 membranes - 2 spotted in duplicate with 62 different non-hematopoietic antibodies and 2 spotted in duplicate with 57 common antibodies
ARY012 
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Proteome Profiler Human XL Oncology Array


Contains 4 membranes-each spotted in duplicate with 84 different cancer-related antibodies
ARY026 
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Proteome Profiler Human Ubiquitin Array


Contains 4 membranes-each spotted in duplicate with 49 different antibodies to ubiquitin target proteins
ARY027 
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