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Erythropoietin: Products

Erythropoietin (Epo) is a 30-kDa, heavily glycosylated protein produced primarily by the kidney. It is the principal factor that regulates erythropoiesis. The production of Epo by kidney cells is increased in response to hypoxia or anemia. The cDNAs for Epo have been cloned from many species. The mature proteins from the various species are highly conserved, exhibiting greater than 80% sequence identity at the amino acid level.

The biological effects of Epo are mediated by the Erythropoietin receptor (Epo R). At the protein sequence level, the human Epo R is approximately 83% identical to the mouse protein. As a result of alternative splicing of the Epo R gene, cDNA clones encoding truncated soluble forms of Epo R have been found. Recombinant soluble Epo R binds Epo with high affinity and is a potent Epo antagonist.

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Human Erythropoietin Antibody

Clonality: Polyclonal
Host: Rabbit IgG
Applications: WB, IHC, B/N
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AB-286-NA

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Cell Proliferation Induced by Erythropoietin and Neutralization by Human Erythropoietin Antibody.
Erythropoietin in Human Kidney Cancer Tissue.

Human Erythropoietin Antibody

Clonality: Monoclonal
Host: Mouse IgG2a Clone #AE7A5
Applications: AP, WB
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MAB2871

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Human Erythropoietin Antibody

Clonality: Monoclonal
Host: Mouse IgG1 Clone #9C21D11
Applications: B/N
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MAB287

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Cell Proliferation Induced by Erythropoietin and Neutralization by Human Erythropoietin Antibody.

Human/Mouse/Rat Erythropoietin Antibody

Clonality: Polyclonal
Host: Goat IgG
Applications: B/N, WB
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AF959

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Cell Proliferation Induced by Erythropoietin and Neutralization by Mouse Erythropoietin Antibody.

Mouse Erythropoietin Antibody

Clonality: Monoclonal
Host: Rat IgG2a Clone #148438
Applications: B/N
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MAB959

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Cell Proliferation Induced by Erythropoietin and Neutralization by Mouse Erythropoietin Antibody.

Mouse Erythropoietin Antibody

Clonality: Monoclonal
Host: Rat IgG2a Clone #148436
Applications: B/N
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MAB9591

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Cell Proliferation Induced by Erythropoietin and Neutralization by Mouse Erythropoietin Antibody.

Human/Mouse/Rat Erythropoietin Biotinylated Antibody

Clonality: Polyclonal
Host: Goat IgG
Applications: WB
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BAF959

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Mouse Erythropoietin Biotinylated Antibody

Clonality: Monoclonal
Host: Rat IgG2b Clone #148409
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BAM9592

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