Fatty acid binding proteins are small cytoplasmic lipid binding proteins that are expressed in a tissue specific manner. FABPs bind free fatty acids, cholesterol, and retinoids, and are involved in intracellular lipid transport. Circulating FABP levels are used as indicators of tissue damage. Some FABP polymorphisms have been associated with disorders of lipid metabolism and the development of atherosclerosis.
Fatty Acid Binding Protein 7 (FABP7) also known as (Brain) B-FABP, Brain lipid-binding protein (BLBP) and mammary-derived growth inhibitor-related (MRG), belongs to the family of intracellular lipid-binding proteins. FABP7 is involved in fatty acid uptake and intracellular transport and is important in brain development. Human FABP7 shares 86% amino acid sequence identity with mouse FABP7.