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FGF R3: Products

FGF R3 (fibroblast growth factor receptor 3), also known as CEK2 and CD333, is a transmembrane receptor tyrosine kinase that plays a role in skeletal development and tumorigenesis. Alternative splicing generates beta isoforms of the receptor which lack the first Ig-like domain as well as IIIb isoforms that have a substitution in the third Ig-like domain. FGF R3 (IIIb) triggers cell proliferation in response to FGF acidic and FGF-9, while FGF R3 (IIIc) shows a wider selectivity that includes FGF acidic, FGF basic, FGF-4, -8, -9, -17, -18, -19, and -20. FGF mediated activation of FGF R3 is dependent on the presence of heparan sulfate proteoglycans. FGF R3 functions as a negative regulator of endochondral bone growth, and FGF R3 mutations are associated with chondrodysplasia in humans. The development of many cancers is associated with mutations or dysregulation of FGF R3.

Showing 1-24 out of 24 FGF R3 Products

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Proteome Profiler Human Phospho-RTK Array Kit


Contains 4 membranes - each spotted in duplicate with 49 different RTK antibodies
ARY001B96  
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Human FGF R3 (IIIc) Antibody


Clone 136312 was used by HLDA to establish CD designation
ICC/IF, IHC, WBMAB76621  
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Human FGF R3 Antibody

B/N, WBMAB76612  
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Human FGF R3 Antibody


Clone 136334 was used by HLDA to establish CD designation
Flow, WBMAB7661  
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Human Phospho-FGF R1-4 (Y653/Y654) Antibody

ICC/IF, WBAF32851  
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Recombinant Human FGF R3 (IIIc) Fc Chimera Protein, CF

 766-FR2  
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Human FGF R3 PerCP-conjugated Antibody


Clone 136334 was used by HLDA to establish CD designation
FlowFAB766C 
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Human FGF R3 Fluorescein-conjugated Antibody


Clone 136334 was used by HLDA to establish CD designation
FlowFAB766F 
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Human FGF R3 PE-conjugated Antibody


Clone 136334 was used by HLDA to establish CD designation
FlowFAB766P1  
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Recombinant Mouse FGF R3 (IIIc) Fc Chimera Protein, CF

 710-MF3  
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PD 173074


FGFR1 and -3 inhibitor
304415  
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Human Phospho-FGF R3 DuoSet IC ELISA

ELISADYC2719-21  
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Recombinant Human FGF R3 (IIIb) Fc Chimera Protein, CF

 1264-FR1  
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Human FGF R3 APC-conjugated Antibody


Clone 136334 was used by HLDA to establish CD designation
FlowFAB766A 
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Mouse FGF R3 Antibody

B/NMAB7101  
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Human FGF R3 (IIIb) Antibody

B/NMAB14741  
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FIIN 1 hydrochloride


Potent, irreversible FGFR inhibitor
4002 
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Recombinant Mouse FGF R3 alpha (IIIb) Fc Chimera Protein, CF

 9089-FR 
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Human Total FGF R3 DuoSet IC ELISA

ELISADYC766-2 
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Mouse FGF R3 (NP_032036) VersaClone cDNA

RDC1204 
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Human FGF R3 (NP_000133) VersaClone cDNA

RDC1195 
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Human FGF R3 (NP_001156685) VersaClone cDNA

RDC1333 
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Mouse FGF R3 (NP_001156689) VersaClone cDNA

RDC1191 
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Proteome Profiler Mouse Phospho-RTK Array Kit


Contains 4 membranes - each spotted in duplicate with 39 different RTK antibodies
ARY0147  
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