FGF-10: Products

FGF-10 (Fibroblast Growth Factor 10) is a heparin binding glycoprotein in the subgroup of FGFs that also includes FGF-3, -7, and -22. FGF-10 is secreted by mesenchymal cells and associates with extracellular FGF-BP. It preferentially binds and activates epithelial cell FGF R2 (IIIb) and interacts more weakly with FGF R1 (IIIb). The mitogenic and chemotactic properties of FGF-10 are critical in limb bud initiation, palate development, branching morphogenesis and directional outgrowth of lung buds, formation of the otic vesicle and chochlea, adipogenesis, and the development of prostate, mammary, lacrimal, and submandibular salivary glands. The expression and function of FGF-10 are negatively regulated by Shh and BMP-4 in the developing lung. Overlapping expression patterns and activities with FGF-3, -7,  and -8 suggest at least a partial redundancy in FGF-10 biology. FGF-10 induced signaling through FGF R2 (IIIb) also contributes to the progression of pancreatic cancer.

Showing 1-11 out of 11 FGF-10 Products

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Recombinant Human FGF-10 Protein

 345-FG21  
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Recombinant Human FGF-10 Protein, CF

 345-FG/CF21  
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Recombinant Mouse FGF-10 Protein

 6224-FG6  
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Recombinant Mouse FGF-10 Protein, CF

 6224-FG/CF6  
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Mouse FGF-10 Antibody

IHC, WBAF6224 
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Human FGF-10 Antibody

IHC, WBAF3451  
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ProDots Recombinant Human FGF-10 Protein


Supplied as ready-to-use 5 ug protein balls
 PRD345 
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Human FGF-10 Antibody

WBMAB3451  
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Human FGF-10 Biotinylated Antibody

WBBAF345 
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Recombinant Rat FGF-10 Protein, CF

 7804-FG/CF 
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Recombinant Rat FGF-10 Protein

 7804-FG 
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