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Fc epsilon RI beta/MS4A2: Products

The allergic response involves the binding of allergen to receptor-bound IgE followed by cell activation and the release of mediators responsible for the manifestations of allergy. The IgE-receptor, a tetramer composed of an alpha, beta, and 2 disulfide-linked gamma chains, is found on the surface of mast cells and basophils. Fc epsilon RI beta/MS4A2 is the beta subunit of the high affinity IgE receptor which is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. Fc epsilon RI beta seems to be a risk factor for atopic dermatitis and asthma.

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Human Fc epsilon RI beta/MS4A2 (NP_000130) VersaClone cDNA

RDC0229 
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Mouse Fc epsilon RI beta/MS4A2 (NP_038544) VersaClone cDNA

RDC0230 
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