Focal Adhesion Kinase Inhibitors: Products

FAK (Focal Adhesion Kinase) is a non-receptor protein tyrosine kinase involved in signal transduction from integrin-enriched focal adhesion sites that mediate cell contact with the extracellular matrix. FAK-enhanced signals have been shown to mediate the survival of anchorage-dependent cells and are critical for efficient cell migration in response to growth factor receptor and integrin stimulation. Elevated expression of FAK in human tumors has been correlated with increased malignancy and invasiveness.

Showing 1-4 out of 4 Focal Adhesion Kinase Inhibitors Products

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PF 573228


Potent and selective FAK inhibitor
323941
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FAK Inhibitor 14


Selective FAK inhibitor
341416
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PF 431396


Dual FAK/PYK2 inhibitor
42786
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Y 11


Potent and selective FAK inhibitor
44982
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