Frizzled-1: Products

This group of G protein-coupled receptors consists of 10 structurally-related, seven transmembrane proteins with a divergent N-terminal signal peptide and a variable-length C-terminal tail. The Frizzled family proteins contain a highly conserved cysteine-rich domain and a variable length linker region. Frizzled proteins function as receptors for Wnt proteins and can activate canonical Wnt/beta-catenin signaling as well as non-canonical pathways (Planar Cell Polarity and Wnt/Ca2+ Pathways). Wnt/Frizzled signaling is involved in a variety of developmental processes including cell fate determination, cell polarity, tissue patterning, and control of cell proliferation. Activation of a given Wnt/Frizzled signaling cascade is dependent on the Wnt ligand and the cell context. Frizzled proteins also form co-receptor complexes with LRP, ROR, and Ryk molecules.

Showing 1-11 out of 11 Frizzled-1 Products

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Mouse Frizzled-1 Antibody

IHC, WBAF11203  
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Human/Mouse Frizzled-1 Antibody

Flow, WBMAB112011  
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Human/Mouse Frizzled-1 Fluorescein-conjugated Antibody

FlowFAB11201F 
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Human/Mouse Frizzled-1 Biotinylated Antibody

Flow, ICC/IF, WBBAM11201 
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Human/Mouse Frizzled-1 APC-conjugated Antibody

FlowFAB11201A 
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Recombinant Mouse Frizzled-1 Fc Chimera Protein, CF

 1120-FZ2  
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Mouse Frizzled-1 Biotinylated Antibody

IHC, WBBAF1120 
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Recombinant Human Frizzled-1 Fc Chimera Protein, CF

 5988-FZ1  
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Mouse Frizzled-1 Antibody

WBMAB1120 
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Human Frizzled-1 (NP_003496) VersaClone cDNA

RDC0117 
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Mouse Frizzled-1 (NP_067432) VersaClone cDNA

RDC0518 
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