Fucosyltransferase 3/5 (FUT3/5): Products

FUT5 (alpha-1, 3-fucosyltransferase 5; also Fuc-TV) is a 43 kDa member of the glycosyltransferase 10 family. It is responsible for the terminal step in the synthesis of Lex, sialy-Lex, and Lea antigens. This is accomplished by the transfer of fucose to preexisting LacNAc or sialyl-LacNAc structures. Human FUT5 is 374 amino acids (aa) in length. It is a type II transmembrane Golgi glycoprotein with a C-terminal lumenal domain (aa 35-374). The catalytic domain spans aa 77-374, while the acceptor-binding motif includes aa 120-126. FUT5 is the product of a single exon gene. Thus, there are no splice variants. FUT5 only occurs in primates; there is no rodent ortholog.

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Human Fucosyltransferase 3/5 (FUT3/5) Lumenal Domain Antibody

IP, WBAF4068 
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Human Fucosyltransferase 3/5 (FUT3/5) Antibody

IP, WBMAB4068 
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