GABA-B R1: Products

The neurotransmitter gamma-aminobutyric acid (GABA) mediates an inhibitory signal upon binding to two ligand-gated channels, GABA-A and GABA-C receptors, and a G protein-coupled receptor (GPCR), GABA-B. The GABA-B receptor is a heterodimeric complex composed of two 7-transmembrane GPCRs termed GABA-B R1 and GABA-B R2. GABA-B receptors have been implicated in the GABA-induced modulation of sympathetic and catecholaminergic pathways in the central nervous system.

Showing 1-22 out of 22 GABA-B R1 Products

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CGP 55845 hydrochloride


Potent, selective GABAB antagonist
124863  
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Human/Mouse/Rat GABAB R1 Antibody

IHC, WBAF7000 
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(R)-Baclofen


Selective GABAB agonist. Active enantiomer of (RS)-Baclofen (Cat. No. 0417)
079610  
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CGP 54626 hydrochloride


Potent, selective GABAB antagonist
108819  
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CGP 35348


Brain penetrant, selective GABAB antagonist
12457  
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CGP 52432


Potent, selective GABAB antagonist
124616  
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Rat GABAB R1 Antibody

IHCMAB7000 
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(RS)-Baclofen


Selective GABAB agonist
041714  
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RuBi GABA trimethylphosphine


Caged GABA; inhibits neural activity
4709 
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SCH 50911


Selective, competitive, orally active GABAB antagonist
09849  
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Saclofen


Selective GABAB antagonist
02469  
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Human GABA-B R1 (NP_001461) VersaClone cDNA

RDC0646 
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Phaclofen


Weak, selective GABAB antagonist
01781  
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2-Hydroxysaclofen


Selective GABAB antagonist, more potent than saclofen (Cat. No. 0246)
02452  
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SKF 97541


Extremely potent GABAB agonist
03796  
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CGP 46381


Brain penetrant, selective GABAB antagonist
12474  
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CGP 7930


Positive modulator at GABAB receptors
15133  
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CGP 13501


Positive modulator at GABAB receptors
1514 
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GS 39783


Positive modulator at GABAB receptors
20012  
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CGP 36216 hydrochloride


GABAB antagonist; displays activity at presynaptic receptors
32191  
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rac BHFF


Potent, selective GABAB positive allosteric modulator
33131  
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UMB 68


GHB receptor ligand
5518 
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