GITR Ligand/TNFSF18: Products

GITR Ligand, also known as TNFSF18 and TL6, is a transmembrane glycoprotein that is expressed on antigen presenting cells, CD4-CD8- double negative thymic precursors, vascular endothelial cells, neurons, and in the eye. Its expression is transiently upregulated by proinflammatory stimulation. The binding of GITR Ligand to GITR on mouse CD25+ Treg cells permits the reactivation of T cells from Treg-induced suppression. GITR Ligand binding to GITR additionally provides a costimulatory signal to activated CD4+  and CD8+ T cells and NK cells. This interaction also induces reverse signaling in GITR Ligand expressing dendritic cells to suppress cellular activation through the same pathway induced by the immunosuppressant dexamethasone. In the brain, GITR Ligand/GITR interactions enhance NGF-mediated neurite outgrowth from sympathetic neurons.

Showing 1-22 out of 22 GITR Ligand/TNFSF18 Products

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Recombinant Human GITR Ligand/TNFSF18 (CHO-expressed), CF

 6987-GL/CF 
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Recombinant Human GITR Ligand/TNFSF18 (CHO-expressed)

 6987-GL 
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Recombinant Human GITR Ligand/TNFSF18 Protein

 694-GL4  
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Recombinant Human GITR Ligand/TNFSF18 Protein, CF

 694-GL/CF4  
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Human GITR Ligand/TNFSF18 Antibody

B/N, ELISA(Cap), FlowMAB69424  
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Recombinant Mouse GITR Ligand/TNFSF18 (aa 47-173), CF

 2177-GL/CF2  
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Recombinant Mouse GITR Ligand/TNFSF18 (aa 47-173) Protein

 2177-GL2  
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Human GITR Ligand/TNFSF18 Antibody

B/N, FlowMAB69415  
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Human GITR Ligand/TNFSF18 Antibody

B/N, Flow, WBAF6941  
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Human GITR Ligand/TNFSF18 PE-conjugated Antibody

FlowFAB6941P1  
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Human GITR Ligand/TNFSF18 Fluorescein-conjugated Antibody

FlowFAB6941F2  
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Mouse GITR Ligand/TNFSF18 Antibody

B/N, ELISA(Cap)MAB2177 
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Mouse GITR Ligand/TNFSF18 Antibody

WBMAB217721  
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Human GITR Ligand/TNFSF18 DuoSet ELISA

ELISADY6943  
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Mouse GITR Ligand/TNFSF18 Biotinylated Antibody

BAF21771  
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Human GITR Ligand/TNFSF18 APC-conjugated Antibody

FlowFAB6941A 
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Human GITR Ligand/TNFSF18 Biotinylated Antibody

BAM69431  
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Human GITR Ligand/TNFSF18 Alexa Fluor® 700-conjugated Antibody

FlowFAB6941N 
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Human GITR Ligand/TNFSF18 PerCP-conjugated Antibody

FlowFAB6941C 
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Human GITR Ligand/TNFSF18 Biotinylated Antibody

Flow, WBBAF694 
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Rat GITR Ligand/TNFSF18 (XP_008767927) VersaClone cDNA

RDC1159 
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Mouse GITR Ligand/TNFSF18 DuoSet ELISA

ELISADY2177 
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