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GITR/TNFRSF18: Products

GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a transmembrane TNF receptor superfamily member that functions in immune regulation. GITR is expressed on CD4+CD25+ regulatory T cells (Treg) as well as on subsets of thymocytes, lymph node cells, and splenocytes, and it is upregulated on antigen-activated conventional CD4+ and CD8+ T cells. GITR binding by GITR Ligand/TNFSF18 costimulates the proliferation and activation of CD4+ or CD8+ conventional T cells. It also induces the proliferation of Treg but inhibits the ability of Treg to suppress immune responses. This can result in the development of autoimmunity, increased tumor cell killing by effector T cells, and increased inflammation in arthritis, allergic asthma, and inflammatory bowel disease. GITR is also expressed on sympathetic neurons where it enhances NGF-induced neurite outgrowth and branching.

Showing 1-27 out of 27 GITR/TNFRSF18 Products

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Human Magnetic Luminex Assay

LXSAHM7  
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Human Luminex Assay

LXSAH4  
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Recombinant Human GITR/TNFRSF18 Fc Chimera Protein, CF

 689-GR 
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Human GITR/TNFRSF18 Antibody

B/N, ELISA(Cap), Flow, WBMAB6895  
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Human GITR/TNFRSF18 PE-conjugated Antibody

FlowFAB689P7  
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Human GITR/TNFRSF18 Antibody

B/N, Flow, IHC, WBAF6891  
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Recombinant Mouse GITR/TNFRSF18 Fc Chimera Protein, CF

 524-GR 
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Human GITR/TNFRSF18 APC-conjugated Antibody

FlowFAB689A3  
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Mouse GITR/TNFRSF18 Antibody

Flow, WBMAB52415  
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Human GITR/TNFRSF18 Biotinylated Antibody

ELISA(Det), WBBAF6891  
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Human GITR/TNFRSF18 Fluorescein-conjugated Antibody

FlowFAB689F3  
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Mouse GITR/TNFRSF18 Antibody

WBAF5244  
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Mouse GITR/TNFRSF18 Biotinylated Antibody

ELISA(Det), WBBAF5243  
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Mouse GITR/TNFRSF18 Fluorescein-conjugated Antibody

FlowFAB5241F2  
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Human GITR/TNFRSF18 Alexa Fluor® 488-conjugated Antibody

FlowFAB689G 
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Mouse GITR/TNFRSF18 PE-conjugated Antibody

FlowFAB5241P1  
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Mouse GITR/TNFRSF18 Antibody

ELISA(Cap), WBMAB524 
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Human GITR/TNFRSF18 Alexa Fluor® 700-conjugated Antibody

FlowFAB689N 
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Human GITR/TNFRSF18 DuoSet ELISA

ELISADY6891  
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Mouse GITR/TNFRSF18 APC-conjugated Antibody

FlowFAB5241A 
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Mouse GITR/TNFRSF18 DuoSet ELISA

ELISADY524 
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Human GITR/TNFRSF18 (NP_004186) VersaClone cDNA

RDC0359 
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Rat GITR/TNFRSF18 (NP_001019520) VersaClone cDNA

RDC1154 
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Mouse GITR/TNFRSF18 (NP_033426) VersaClone cDNA

RDC1541 
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Recombinant Rat GITR/TNFRSF18 Fc Chimera, CF

 9130-GR 
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Cynomolgus Monkey GITR/TNFRSF18 XP_005545180 VersaClone cDNA

RDC1695 
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Proteome Profiler Human NFkB Pathway Array Kit


Contains 4 membranes-each spotted in duplicate with 41 different proteins and 4 serine or tyrosine phosphorylation sites antibodies
ARY029 
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