Filter Results
clear

By Category

By Common Name

clear

By Species

clear

By Gene Symbol

clear

By Brand

GPR4: Products

The activation of GPR4, a proton-sensing G protein-coupled receptor, by isocapnic acidosis increases the adhesiveness of human umbilical vein endothelial cells (HUVECs) that express GPR4 endogenously. Acidosis in combination with GPR4 overexpression further augments HUVEC adhesion with U937 monocytes. Activation of GPR4 increases the expression of vascular adhesion molecules E-selectin, VCAM-1 and ICAM-1, which are functionally involved in acidosis/GPR4-mediated HUVEC adhesion. Acidosis/GPR4 signaling regulates endothelial cell adhesion mainly through the G(s)/cAMP/Epac pathway and may play a role in the inflammatory response of vascular endothelial cells.

Showing 1-3 out of 3 GPR4 Products

page of 1
Results Per Page
DescriptionApplicationCat#CitationsImages 

Human GPR4 (NP_005273) VersaClone cDNA

RDC0300 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Human GPR4 (AAA63180) VersaClone cDNA

RDC0299 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Mouse GPR4 (NP_783599) VersaClone cDNA

RDC0777 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....
page of 1
Results Per Page