GPR55 Receptor Agonists: Products

Members of the G protein-coupled receptor (GPCR) family, such as GPR55, play important roles in signal transduction from the external environment to the inside of the cell. GPR55 is a receptor for L-alpha-lysophosphatidylinositol (LPI). LPI induces Ca2+ release from intracellular stores via the heterotrimeric G protein GNA13 and RHOA. GPR55 is expressed in the caudate nucleus and putamen, but not detected in the hippocampus, thalamus, pons cerebellum, frontal cortex of the brain or in the liver. It is expressed in osteoclasts and osteoblasts. GPR55 may play a role in bone physiology by regulating osteoclast number and function. GPR55 may also be involved in hyperalgesia associated with inflammatory and neuropathic pain.

Showing 1-6 out of 6 GPR55 Receptor Agonists Products

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AM 251


Potent CB1 antagonist; also GPR55 agonist
1117112  
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O-1602


Potent GPR55 receptor agonist
27975  
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Oleylethanolamide


Lipid mediator, anorexic actions; also GPR55 and PPARalpha agonist
14843  
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Abn-CBD


Selective GPR55 agonist; neurobehaviorally inactive
12973  
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Noladin ether


Endogenous agonist for CB1 and GPR55. Restrictions apply. See special conditions on product page.
14111  
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Palmitoylethanolamide


Selective GPR55 agonist. FAAH and PAA substrate
08797  
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