GSK-3 alpha: Products

GSK-3 is a Ser/Thr kinase first identified as an inactivator of Glycogen Synthase. GSK-3 acts as a multifunctional downstream switch that determines the output of numerous signaling pathways. There are two mammalian GSK-3 isoforms encoded by distinct genes, GSK-3 alpha and GSK-3 beta, which are structurally similar, but functionally non-identical. GSK-3a is inhibited by phosphorylation at S21 by Akt and other kinases. GSK-3 alpha and GSK-3 beta share 85% amino acid identity. Dysregulated GSK-3 has been implicated in several diseases including type II diabetes, Alzheimers disease, bipolar disorder, and cancer.

Showing 1-15 out of 15 GSK-3 alpha Products

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CHIR 99021


Highly selective GSK-3 inhibitor
442331  
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Human/Mouse/Rat Phospho-GSK-3 alpha / beta (S21/S9) Antibody

Flow, ICC/IF, WBAF15903  
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Human/Mouse/Rat GSK-3 alpha / beta Antibody

Flow, ICC/IF, WBAF21571  
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Human/Mouse/Rat Phospho-GSK-3 alpha (S21) Antibody

IHC, WBAF41251  
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CHIR 99021 trihydrochloride


Hydrochloride salt of CHIR 99021 (Cat. No. 4423); selective GSK-3 inhibitor
4953 
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Human GSK-3 alpha / beta Antibody

WBMAB25063 
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MeBIO


Inactive analog of BIO (Cat. No. 3194)
3873 
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Human GSK-3 alpha Antibody

ICC/IFMAB2986 
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Total GSK-3 alpha/beta DuoSet IC ELISA

ELISADYC2157-2 
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Phospho-GSK-3 alpha/beta (S21/S9) DuoSet IC ELISA

ELISADYC2630-2 
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BIO-acetoxime


Selective GSK-3alpha/beta inhibitor
38741  
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GSK J2


Inactive isomer of GSK J1 (Cat. No. 4593)
4688 
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AR-A 014418


Selective GSK-3 inhibitor
39662  
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A 1070722


Highly potent, selective GSK-3 inhibitor
4431 
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Human Phospho-GSK-3 alpha (S21) DuoSet IC ELISA

ELISADYC4125-2 
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