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GSK-3 alpha/beta: Products

GSK-3 is a Ser/Thr kinase first identified as an inactivator of Glycogen Synthase. GSK-3 acts as a multifunctional downstream switch that determines the output of numerous signaling pathways. There are two mammalian GSK-3 isoforms encoded by distinct genes, GSK-3 alpha and GSK-3 beta, which are structurally similar, but functionally non-identical. GSK-3a is inhibited by phosphorylation at S21 by Akt and other kinases. GSK-3 alpha and GSK-3 beta share 85% amino acid identity. Dysregulated GSK-3 has been implicated in several diseases including type II diabetes, Alzheimer's disease, bipolar disorder, and cancer.

Showing 1-24 out of 24 GSK-3 alpha/beta Products

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DescriptionApplicationCat#CitationsImages 

CHIR 99021


Highly selective GSK-3 inhibitor
442331  
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Proteome Profiler Human Phospho-Kinase Array Kit


Contains 4 sets of 2 membranes - each spotted in duplicate with antibodies against 43 different kinases and 2 related total proteins
ARY003B75  
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SB 216763


Potent, selective GSK-3 inhibitor
161650  
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Human/Mouse/Rat Phospho-GSK-3 alpha / beta (S21/S9) Antibody

Flow, ICC/IF, WBAF15903  
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Human/Mouse/Rat GSK-3 alpha / beta Antibody

Flow, ICC/IF, WBAF21571  
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BIO


Potent, selective GSK-3 inhibitor
319410  
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Kenpaullone


Potent cyclin-dependent kinase inhibitor. Also inhibits GSK-3
13982  
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Proteome Profiler Human Phospho-MAPK Array Kit


Contains 4 membranes - each spotted in duplicate with 26 different MAPK antibodies
ARY002B54  
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Human GSK-3 alpha / beta Antibody

WBMAB25063 
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TCS 2002


Potent GSK-3beta inhibitor
3869 
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SB 415286


Potent, selective GSK-3 inhibitor
161720  
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Total GSK-3 alpha/beta DuoSet IC ELISA

ELISADYC2157-2 
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Phospho-GSK-3 alpha/beta (S21/S9) DuoSet IC ELISA

ELISADYC2630-2 
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BIO-acetoxime


Selective GSK-3alpha/beta inhibitor
38741  
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AR-A 014418


Selective GSK-3 inhibitor
39662  
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A 1070722


Highly potent, selective GSK-3 inhibitor
4431 
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3F8


Potent and selective GSK-3beta inhibitor
4083 
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TCS 21311


Potent JAK3 inhibitor. Also inhibits GSK-3beta and PKC
4221 
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Phospho-Glycogen Synthase Peptide-2 (substrate)


Glycogen synthase kinase-3 substrate (synthetic)
13521  
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Indirubin-3'-oxime


GSK-3beta inhibitor. Also inhibits other protein kinases
1813 
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L803


Substrate-competitive inhibitor of GSK-3
2235 
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NSC 693868


Cdk inhibitor. Also inhibits GSK-3
1937 
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TWS 119


GSK-3beta inhibitor; induces neuronal differentiation in ESCs
3835 
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L803-mts


Selective inhibitor of GSK-3
22561  
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