IGF-II: Products

IGF-II (Insulin-like growth factor II; also multiplication-stimulating polypeptide/MSP and somatomedin-A) belongs to the insulin family of peptide growth factors. It is part of a complex system of growth and metabolic-regulating proteins that is particularly important during development. It has been associated with nervous system proliferation and differentiation, myelination, adrenal cortical proliferation, and skeletal growth and differentiation. In human, IGF-II is primarily synthesized by the liver, and circulates at high levels in both fetus and adult. In rodent, however, IGF-II levels drop after the perinatal period. IGF-II is produced by astrocytes, hepatocytes, osteoblasts, embryonic striated muscle cells plus Kupffer cells and Ito cells. IGF-II binds to IGF-I R, Insulin R (IR)-type A, IGF-I R:Insulin R-A hybrids, IGF-II R, and IGF binding proteins 1-6. The first three receptors initiate downstream signaling events, the IGF-II R sequesters local IGF-II, and the six IGFBPs regulate IGF-II activity in various tissues.

Showing 1-15 out of 15 IGF-II Products

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Recombinant Human IGF-II Protein, CF

 292-G2 
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Recombinant Mouse IGF-II Protein, CF

 792-MG 
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Human IGF-II Antibody

B/N, IHC, WBAF-292-NA 
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Mouse IGF-II Antibody

B/N, IHC, WBAF792 
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Mouse IGF-II Antibody

ELISA(Cap), WBMAB792 
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Human IGF-II Antibody

B/NMAB292 
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Mouse IGF-II DuoSet ELISA

ELISADY792 
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Mouse IGF-II Biotinylated Antibody

ELISA(Det), WBBAF792 
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Human IGF-II Biotinylated Antibody

WBBAF292 
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Human IGF-II Quantikine ELISA Kit

ELISADG200 
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Human IGF-II Antibody

WBMAB2921 
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Quantikine Immunoassay Control Set 918 for Human IGF-II


For use with catalog number DG200
QC230 
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Proteome Profiler Mouse Angiogenesis Array Kit


Contains 4 membranes - each spotted in duplicate with 53 different cytokine antibodies
ARY015 
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Proteome Profiler Mouse Adipokine Array Kit


Contains 4 membranes - each spotted in duplicate with 38 different obesity-related antibodies
ARY013 
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Proteome Profiler Rat Adipokine Array Kit


Contains 4 membranes - each spotted in duplicate with 30 different obesity-related antibodies
ARY016 
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