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IL-1 RII: Products

Two distinct types of receptors that bind the pleiotropic cytokines IL-1 alpha and IL-1 beta have been described. The IL-1 receptor Type I is an 80 kDa transmembrane protein that is expressed predominantly by T cells, fibroblasts, and endothelial cells. IL-1 receptor Type II is a 68 kDa transmembrane protein found on B lymphocytes, neutrophils, monocytes, large granular leukocytes and, endothelial cells. Both receptors are members of the immunoglobulin superfamily and show approximately 28% sequence similarity in their extracellular domains. The two receptor types do not heterodimerize in a receptor complex.

IL-1 RII has a short cytoplasmic domain and does not transduce IL-1 signals. In addition to the membrane-bound form of IL-1 RII, a naturally-occurring soluble form of IL-1 RII has been described. It has been suggested that the Type II receptor, either as the membrane-bound or as the soluble form, serves as a decoy for IL-1 and inhibits IL-1 action by blocking the binding of IL-1 to the signaling Type I receptor complex. Recombinant IL-1 soluble receptor type II is a potent antagonist of IL-1 action.

Showing 1-26 out of 26 IL-1 RII Products

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Human Magnetic Luminex Assay

LXSAHM7  
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Human Luminex Assay

LXSAH4  
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Human IL-1 RII Quantikine ELISA Kit

ELISADR1B0012  
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Human IL-1 RII Antibody

B/N, ICC/IF, WBAF-263-NA3  
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Human IL-1 RII Antibody

B/N, ELISA(Cap), WBMAB6631  
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Human IL-1 RII Antibody

B/N, ICC/IF, WBMAB2632  
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Recombinant Human IL-1 RII Protein

 263-2R4  
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Recombinant Human IL-1 RII Protein, CF

 263-2R/CF4  
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Mouse IL-1 RII Antibody

Flow, IHC, WBAF5631  
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Human IL-1 RII Biotinylated Antibody

ELISA(Det), WBBAF2632  
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Human IL-1 RII PE-conjugated Antibody

FlowFAB663P1  
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Human IL-1 RII DuoSet ELISA

ELISADY2632  
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Human IL-1 RII APC-conjugated Antibody

FlowFAB663A 
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Human IL-1 RII Antibody

WBMAB2631 
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Human IL-1 RII Fluorescein-conjugated Antibody

FlowFAB663F 
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Mouse IL-1 RII Biotinylated Antibody

WBBAF5631  
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Recombinant Mouse IL-1 RII Fc Chimera Protein, CF

 563-MR1  
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Recombinant Human IL-1 RII Fc Chimera Protein, CF

 663-2R 
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Mouse IL-1 RII Alexa Fluor® 488-conjugated Antibody

FlowFAB563G 
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Mouse IL-1 RII Antibody

WBMAB563 
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Human IL-1 RII PerCP-conjugated Antibody

FlowFAB663C 
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Human IL-1 RII Alexa Fluor® 700-conjugated Antibody

FlowFAB663N 
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Mouse IL-1 RII (NP_034685) VersaClone cDNA

RDC1140 
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Human IL-1 RII (NP_004624) VersaClone cDNA

RDC1142 
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Proteome Profiler Human sReceptor Array, Non-hematopoietic


Contains 4 membranes - 2 spotted in duplicate with 62 different non-hematopoietic antibodies and 2 spotted in duplicate with 57 common antibodies
ARY0128  
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Proteome Profiler Human sReceptor Array, Hematopoietic


Contains 4 membranes - 2 spotted in duplicate with 48 different hematopoietic antibodies and 2 spotted in duplicate with 57 common antibodies
ARY0111  
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