IL-12 R beta 1: Products

The biological activities of IL-12 are mediated through a receptor complex composed of two class I cytokine receptor subunits designated IL-12 R beta 1 and IL-12 R beta 2. Both subunits are required for high-affinity binding and activity of IL-12. IL-12 R beta 1 binds specifically to IL-12 p40, a subunit of the heterodimeric IL-12, and is also a subunit of the IL-23 receptor complex, while IL-12 R beta 2 binds IL-12 p35. IL-12 Rs are predominantly expressed on NK cells and activated T (Th1) cells with some expression also on dendritic cells. Both IL-12 R subunit extracellular domains are composed of three fibronectin-like domains and two cytokine receptor homology domains. IL-12R beta 2 also has an extracellular Ig-like domain.

Showing 1-16 out of 16 IL-12 R beta 1 Products

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Recombinant Human IL-12 R beta 1 Fc Chimera Protein, CF

 839-B11  
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Human IL-12 R beta 1 PE-conjugated Antibody

FlowFAB839P3  
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Human IL-12 R beta 1 Antibody

WBAF8393  
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Mouse IL-12 R beta 1 Antibody

WBAF19981  
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Mouse IL-12 R beta 1 Biotinylated Antibody

WBBAF1998 
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Human IL-12 R beta 1 Alexa Fluor® 700-conjugated Antibody

FlowFAB839N 
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Human IL-12 R beta 1 Biotinylated Antibody

WBBAF839 
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Mouse IL-12 R beta 1 PE-conjugated Antibody

FlowFAB1998P 
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Human IL-12 R beta 1 Fluorescein-conjugated Antibody

FlowFAB839F 
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Human IL-12 R beta 1 Antibody

FlowMAB8391  
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Human IL-12 R beta 1 PerCP-conjugated Antibody

FlowFAB839C 
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Human IL-12 R beta 1 APC-conjugated Antibody

FlowFAB839A 
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Mouse IL-12 R beta 1 Fluorescein-conjugated Antibody

FlowFAB1998F 
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Recombinant Mouse IL-12 R beta 1 Protein, CF

 1998-B1 
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Human IL-12 R beta 1 (NP_005526) VersaClone cDNA

RDC1160 
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Mouse IL-12 R beta 1 (NP_032379) VersaClone cDNA

RDC1348 
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