IL-12 R beta 2: Products

The biological activities of IL-12 are mediated through a receptor complex composed of two class I cytokine receptor subunits designated IL-12 R beta 1 and IL-12 R beta 2. Both subunits are required for high-affinity binding and activity of IL-12. IL-12 R beta 1 binds specifically to IL-12 p40, a subunit of the heterodimeric IL-12, and is also a subunit of the IL-23 receptor complex, while IL-12 R beta 2 binds IL-12 p35. IL-12 Rs are predominantly expressed on NK cells and activated T (Th1) cells with some expression also on dendritic cells. Both IL-12 R subunit extracellular domains are composed of three fibronectin-like domains and two cytokine receptor homology domains. IL-12R beta 2 also has an extracellular Ig-like domain.

Showing 1-12 out of 12 IL-12 R beta 2 Products

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Human/Mouse IL-12 R beta 2 PE-conjugated Antibody

FlowFAB1959P1  
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Human/Mouse IL-12 R beta 2 Alexa Fluor® 488-conjugated Antibody

FlowFAB1959G 
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Human/Mouse IL-12 R beta 2 APC-conjugated Antibody

FlowFAB1959A1  
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Recombinant Human IL-12 R beta 2 Fc Chimera Protein, CF

 1959-B2 
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Human IL-12 R beta 2 Antibody

WBMAB19591 
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Human IL-12 R beta 2 Antibody

B/N, WBAF1959 
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Mouse IL-12 R beta 2 Antibody

B/NMAB8650 
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Human/Mouse IL-12 R beta 2 PerCP-conjugated Antibody

FlowFAB1959C 
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Recombinant Mouse IL-12 R beta 2 Fc Chimera Protein, CF

 7406-MR 
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Human IL-12 R beta 2 Biotinylated Antibody

WBBAF1959 
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Human IL-12 R beta 2 (NP_001550) VersaClone cDNA

RDC1184 
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Mouse IL-12 R beta 2 (NP_032380) VersaClone cDNA

RDC1169 
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