IL-13 R alpha 1: Products

Two members of the type 5 subfamily of type I cytokine receptors can serve as receptors for IL-13. IL-13 can bind to IL-13 R alpha 1 (CD213a1; previously designated IL-13 R alpha or NR4) with low affinity, then recruits the IL-4 R alpha chain to form a high affinity receptor, causing downstream STAT6 activation. Alternately, IL-13 can bind IL-13 R alpha 2 (CD213a2) with high affinity; this interaction does not cause activation of STAT6, but does induce TGF-beta production. IL-13 R alpha 1 and IL-13 R alpha 2 each have three extracellular fibronectin type III domains, two cytokine receptor homology modules and a WSXWS motif typical of the class I cytokine receptor family, but IL-13 R alpha 2 has a much shorter cytoplasmic tail. IL-13 R subunits can be expressed on monocytes, macrophages, fibroblasts, human B cells, basophils, eosinophils, endothelial cells, and smooth muscle cells.

Showing 1-15 out of 15 IL-13 R alpha 1 Products

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Human IL-13 R alpha 1 Antibody

B/N, Flow, IHC, WBAF1525  
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Human IL-13 R alpha 1 Antibody

Flow, WBMAB14622  
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Human IL-13 R alpha 1 Biotinylated Antibody

ELISA(Det), Flow, WBBAF1521  
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Recombinant Human IL-13 R alpha 1 Fc Chimera Protein, CF

 146-IR2  
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Human IL-13 R alpha 1 Antibody

ELISA(Cap), WBMAB1462  
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Human IL-13 R alpha 1 Alexa Fluor® 700-conjugated Antibody

FlowFAB1462N1  
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Human IL-13 R alpha 1 Fluorescein-conjugated Antibody

FlowFAB1462F1  
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Human IL-13 R alpha 1 PE-conjugated Antibody

FlowFAB1462P1  
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Human IL-13 R alpha 1 PerCP-conjugated Antibody

FlowFAB1462C 
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Human IL-13 R alpha 1 APC-conjugated Antibody

FlowFAB1462A 
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Recombinant Mouse IL-13 R alpha 1 Fc Chimera Protein, CF

 491-IR/CF 
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Recombinant Mouse IL-13 R alpha 1 Fc Chimera Protein

 491-IR 
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Human IL-13 R alpha 1 (NP_001551) VersaClone cDNA

RDC1305 
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Human IL-13 R alpha 1 DuoSet ELISA

ELISADY152 
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Mouse IL-13 R alpha 1 (NP_598751) VersaClone cDNA

RDC1357 
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