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IL-18 R alpha/IL-1 R5: Products

Interleukin-18 (IL-18) is a member of the IL-1 family of cytokines and shares numerous immuno-regulatory functions with IL-12. The functional IL-18 receptor complex is composed of two subunits designated IL18 R alpha (also termed IL-1 R5 and IL-1 Rrp) and IL-18 R beta (also termed IL-1 R7 and AcPL). Both IL-18 R alpha and IL-18 R beta belong to the IL-1 receptor superfamily. Although IL-18 R by itself binds IL-18 with low affinity and IL-18 R beta does not bind IL18 in vitro, coexpression of IL-18 R alpha and IL18 R beta is required for high affinity binding and IL-18 responsiveness.

Human IL-18 R cDNA encodes a 541 amino acid (aa) precursor type I membrane protein with a hydrophobic signal, an extracellular domain comprised of three immunoglobulin-like domains, a transmembrane domain and a cytoplasmic region of approximately 200 aa residues. Human and mouse IL-18 R share 65% amino acid sequence homology. IL-18 R is widely expressed in numerous tissues including spleen, thymus, leukocyte, liver, lung, heart, small and large intestine, prostate and placenta.

Showing 1-18 out of 18 IL-18 R alpha/IL-1 R5 Products

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Human IL-18 R alpha /IL-1 R5 Antibody

B/N, Flow, ICC/IF, IHCMAB8407  
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Human IL-18 R alpha /IL-1 R5 Antibody

B/N, Flow, IHC, WBAF8405  
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Mouse IL-18 R alpha /IL-1 R5 Antibody

B/N, Flow, WBAF8567  
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Human IL-18 R alpha /IL-1 R5 PE-conjugated Antibody

FlowFAB840P5  
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Mouse IL-18 R alpha /IL-1 R5 Antibody

B/N, WBMAB121613  
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Mouse IL-18 R alpha/IL-1 R5 Biotinylated Antibody

WBBAF8564  
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Mouse IL-18 R alpha /IL-1 R5 Antibody

Flow, WBMAB12161  
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Recombinant Human IL-18 R alpha/IL-1 R5 Fc Chimera, CF

 816-LR2  
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Human IL-18 R alpha /IL-1 R5 Antibody

WBMAB84011  
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Human IL-18 R alpha/IL-1 R5 Biotinylated Antibody

Flow, WBBAF840 
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Human IL-18 R alpha /IL-1 R5 APC-conjugated Antibody

FlowFAB840A 
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Mouse IL-18 R alpha /IL-1 R5 APC-conjugated Antibody

FlowFAB1216A 
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Mouse IL-18 R alpha /IL-1 R5 Fluorescein-conjugated Antibody

FlowFAB1216F 
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Human IL-18 R alpha /IL-1 R5 PerCP-conjugated Antibody

FlowFAB840C 
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Human IL-18 R alpha/IL-1 R5 (NP_003846) VersaClone cDNA

RDC1117 
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Proteome Profiler Human NFkB Pathway Array Kit


Contains 4 membranes-each spotted in duplicate with 41 different proteins and 4 serine or tyrosine phosphorylation sites antibodies
ARY029 
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