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IL-18/IL-1F4: Products

IL-18 (Interleukin-18) is secreted by macrophages, dendritic cells, and epithelial cells. Circulating mature IL-18 is sequestered by soluble IL-18 binding proteins (IL-18 BP) that inhibit IL-18 bioactivity. IL-18 signals through a receptor complex that contains IL-18 R alpha IL-18 R beta. It synergizes with other cytokines to activate NK, Th1, and Th17 cells and to increase the production of IFN-gamma. It can also promote Th2 cytokine release which reduces the effectiveness of antiviral responses. Increased levels of active IL-18 contribute to the severity of autoimmunity and hypertension, while deficiency of IL-18 results in symptoms of metabolic syndrome. In cancer, IL-18 stimulates Th1 and NK cells to target tumor cells, but it can also promote angiogenesis, metastasis, and tumor cell immune evasion.

Showing 1-50 out of 51 IL-18/IL-1F4 Products

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Human Magnetic Luminex Assay

LXSAHM7  
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Recombinant Human IL-18/IL-1F4 Protein, CF

 9124-IL/CF 
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Recombinant Human IL-18/IL-1F4 Protein

 9124-IL 
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Human IL-18/IL-1F4 Antibody


Recombinant Monoclonal Antibody.
B/NMAB9124 
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Human IL-18/IL-1F4 ELISA

ELISA762036  
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Recombinant Mouse IL-18/IL-1F4, CF

 9139-IL/CF 
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Recombinant Mouse IL-18/IL-1F4

 9139-IL 
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Recombinant Human IL-18/IL-1F4 Protein

 B001-520  
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Human IL-18/IL-1F4 Antibody

B/N, ELISA(Cap), IPD044-311  
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Human Luminex Assay

LXSAH4  
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Mouse IL-18/IL-1F4 ELISA

ELISA762520  
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Recombinant Mouse IL-18/IL-1F4 Protein

 B002-515  
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Human IL-18/IL-1F4 Antibody

IPD045-31  
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Human IL-18/IL-1F4 Biotinylated Antibody

D045-65  
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Recombinant Mouse IL-18/IL-1F4 Protein, CF

 B004-23  
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Recombinant Mouse IL-18/IL-1F4 Protein, CF

 B004-53  
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Recombinant Human IL-18/IL-1F4 Protein, CF

 B003-52  
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Recombinant Human IL-18/IL-1F4 Protein, CF

 B003-22  
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Rat IL-18/IL-1F4 Antibody

B/N, WBAF5214  
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Proteome Profiler Human Cytokine Array Kit


Contains 4 membranes - each spotted in duplicate with 36 different cytokine antibodies
ARY005B83  
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Recombinant Porcine IL-18/IL-1F4 Protein

 588-PL3  
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Recombinant Porcine IL-18/IL-1F4 Protein, CF

 588-PL/CF3  
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Rat Magnetic Luminex Assay

LXSARM 
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Mouse IL-18/IL-1F4 Antibody

ELISA(Cap), IPD047-33  
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Recombinant Rat IL-18/IL-1F4 Protein

 521-RL3  
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Recombinant Rat IL-18/IL-1F4 Protein, CF

 521-RL/CF3  
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Human IL-18/IL-1F4 Antibody

WBD043-33  
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Mouse IL-18/IL-1F4 Antibody

B/N, IPD048-33  
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Mouse IL-18/IL-1F4 Biotinylated Antibody

D048-62  
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Human/Rhesus Macaque IL-18/IL-1F4 Antibody

B/N, ICC/IF, WBAF2548 
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Human IL-18/IL-1F4 Propeptide Antibody

Flow, WBMAB6462  
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Human IL-18/IL-1F4 Propeptide Antibody

WBAF6463  
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Rat IL-18/IL-1F4 Antibody

WBMAB5212  
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Rat IL-18/IL-1F4 Biotinylated Antibody

WBBAF5212  
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Human Total IL-18/IL-1F4 Quantikine ELISA Kit

ELISADL180 
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Mouse IL-18/IL-1F4 Antibody

WBD046-31  
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Porcine IL-18/IL-1F4 Biotinylated Antibody

WBBAF588 
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Recombinant Rhesus Macaque IL-18/IL-1F4 Protein

 2548-RM 
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Porcine IL-18/IL-1F4 Antibody

ICC/IF, WBAF588 
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Human IL-18/IL-1F4 Propeptide PE-conjugated Antibody

FlowIC646P 
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Feline IL-18/IL-1F4 Antibody

B/N, WBAF5989 
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Canine IL-18/IL-1F4 Antibody

ICC/IF, WBAF2924 
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Recombinant Rhesus Macaque IL-18/IL-1F4 Protein, CF

 2548-RM/CF 
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Canine IL-18/IL-1F4 Antibody

ICC/IF, WBMAB29241 
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Rat Luminex Assay

LXSAR1  
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Canine IL-18/IL-1F4 Antibody

WBMAB2924 
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Human IL-18/IL-1F4 Antibody

B/NMAB91241 
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Recombinant Feline IL-18/IL-1F4 Protein, CF

 5989-RM/CF 
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Recombinant Feline IL-18/IL-1F4 Protein

 5989-RM 
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Human Total IL-18 DuoSet ELISA

ELISADY318-05 
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