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IL-34: Products

Interleukin 34 (IL-34; also known as uncharacterized protein C16orf77) is secreted as a homodimer consisting of 39 kDa monomers. It belongs to no known cytokine family. Human IL-34 is synthesized as a 242 amino acid (aa) precursor that contains a 20 aa signal sequence and a 222 aa mature chain. The mature chain contains one potential site of N-linked glycosylation. Human IL-34 is 71% identical to mouse IL-34 on the amino acid level.

IL-34 is expressed in various tissues, including the heart, brain, liver, kidney, spleen, thymus, testes, ovary, small intestine, prostate, and colon, and is most abundant in the spleen . The receptor for IL-34 is colony-stimulating factor 1 receptor (CSF-1R). IL-34 stimulates monocyte proliferation. In functional studies, IL-34, like CSF-1, the other ligand for CSF-1R, stimulated phosphorylation of extracellular signal-regulated kinase-1 and -2 (ERK1/2) in human monocytes. In addition, IL-34 promoted the formation of the colony-forming unit-macrophage (CFU-M), a macrophage progenitor, in human bone marrow cultures.

Showing 1-19 out of 19 IL-34 Products

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Human Magnetic Luminex Assay

LXSAHM7  
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Build your own with our Luminex Assay Customization Tool.

Human Luminex Assay

LXSAH4  
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Recombinant Human IL-34 Protein, CF

 5265-IL/CF2  
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Recombinant Human IL-34 Protein

 5265-IL2  
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Recombinant Mouse IL-34 Protein, CF

 5195-ML/CF4  
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Recombinant Mouse IL-34 Protein

 5195-ML4  
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Human IL-34 Quantikine ELISA Kit

ELISAD3400 
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Mouse IL-34 Antibody

B/N, WBAF51953  
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Human IL-34 Antibody

B/N, WBAF52651  
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Mouse IL-34 Quantikine ELISA Kit

ELISAM34001  
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Human IL-34 PE-conjugated Antibody

FlowIC5265P1  
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Proteome Profiler Human XL Cytokine Array Kit


Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies
ARY022B5  
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Human IL-34 Antibody

B/N, FlowMAB5265 
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Mouse IL-34 Antibody

B/NMAB5195 
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Quantikine Immunoassay Control Set 766 for Human IL-34


For use with catalog number D3400
CtrlQC31 
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Human IL-34 Antibody

MAB52651 
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Human IL-34 DuoSet ELISA

ELISADY5265B 
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Human IL-34 Biotinylated Antibody

BAM52652 
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Human IL-34 Biotinylated Antibody

WBBAF5265 
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