IL-1 beta/IL-1F2: Products

IL-1 beta (Interleukin-1 beta) is produced in response to inflammatory agents, infections, or microbial endotoxins. It plays a central role in immune and inflammatory responses, bone remodeling, fever, carbohydrate metabolism, and GH/IGF-I physiology. IL-1 beta dysregulation is implicated in many pathological conditions including sepsis, rheumatoid arthritis, inflammatory bowel disease, acute and chronic myelogenous leukemia, insulin-dependent diabetes mellitus, atherosclerosis, neuronal injury, and aging-related diseases. Intracellular cleavage of the IL-1 beta precursor by Caspase-1/ICE is a key step in the inflammatory response. IL-1 beta binds to IL-1 RI and IL-1 RII. The IL-1 receptor accessory protein (IL-1 RAcP) associates with IL-1 RI and is required for IL-1 RI signal transduction, and IL-1ra is a secreted molecule that functions as a competitive inhibitor of IL-1 bioactivity.

Showing 1-17 out of 17 IL-1 beta/IL-1F2 Products

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DLB5084  
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MLB00C141  
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DY40172  
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DY20136  
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RLB0043  
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HSLB00C18  
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PLB00B23  
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DY50118  
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DLBP0013  
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DY6816  
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QLB00B5  
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DY3340 
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DY17962  
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DY3747 
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DY6226 
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For use with catalog number QLB00B
QC190 
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For use with catalog number DLBP00
QC145 
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