IL-1 beta/IL-1F2: Products

IL-1 beta (Interleukin-1 beta) is produced in response to inflammatory agents, infections, or microbial endotoxins. It plays a central role in immune and inflammatory responses, bone remodeling, fever, carbohydrate metabolism, and GH/IGF-I physiology. IL-1 beta dysregulation is implicated in many pathological conditions including sepsis, rheumatoid arthritis, inflammatory bowel disease, acute and chronic myelogenous leukemia, insulin-dependent diabetes mellitus, atherosclerosis, neuronal injury, and aging-related diseases. Intracellular cleavage of the IL-1 beta precursor by Caspase-1/ICE is a key step in the inflammatory response. IL-1 beta binds to IL-1 RI and IL-1 RII. The IL-1 receptor accessory protein (IL-1 RAcP) associates with IL-1 RI and is required for IL-1 RI signal transduction, and IL-1ra is a secreted molecule that functions as a competitive inhibitor of IL-1 bioactivity.

Showing 1-41 out of 41 IL-1 beta/IL-1F2 Products

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B/N, ICC/IF, IHC, SW, WBAF-401-NA34  
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ELISA(Det), ICC/IF, WBBAF20117  
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ELISA(Det), WBBAF40111  
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B/N, ELISA(Cap), ICC/IF, WBMAB60117  
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B/N, ICC/IF, WBAF-201-NA9  
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B/N, ELISA(Cap), ICC/IF, WBAF-501-NA19  
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B/N, Flow, ICC/IF, WBMAB20110  
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B/N, ELISA(Cap)MAB40115  
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ELISA(Det), ICC/IF, WBBAF5012  
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B/N, SW, WBAB-401-NA4  
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B/N, WBAF6812  
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B/N, ICC/IF, WBAB-201-NA1  
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B/N, ELISA(Cap), WBMAB68112  
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ICC/IF, SW, WBMAB6964 
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B/N, IP, WBMAB40122  
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B/N, ICC/IFMAB5012  
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FlowIC201F4  
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WBMAB40112  
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ELISA(Det), WBBAF6811  
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ELISA(Det), ICC/IF, WBBAF1796 
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B/N, WBMAB6813  
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B/N, ICC/IF, WBAF3340 
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FlowIC201P4  
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B/N, ELISA(Cap), ICC/IF, WBAF1796 
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B/N, Flow, WBAF37471  
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WBMAB50111  
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FlowIC4013P 
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B/N, WBAF1009 
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FlowIC8406P 
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B/NMAB8049 
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FlowIC4013A 
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FlowIC201C 
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FlowIC8406A 
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FlowIC4013C 
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FlowIC201A 
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ICC/IFMAB33401 
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WBMAB3340 
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Flow, WBBAF3747 
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FlowMAB4013 
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FlowIC4013F 
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ICC/IFNL201R 
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