IL-1 beta/IL-1F2: Products

IL-1 beta (Interleukin-1 beta) is produced in response to inflammatory agents, infections, or microbial endotoxins. It plays a central role in immune and inflammatory responses, bone remodeling, fever, carbohydrate metabolism, and GH/IGF-I physiology. IL-1 beta dysregulation is implicated in many pathological conditions including sepsis, rheumatoid arthritis, inflammatory bowel disease, acute and chronic myelogenous leukemia, insulin-dependent diabetes mellitus, atherosclerosis, neuronal injury, and aging-related diseases. Intracellular cleavage of the IL-1 beta precursor by Caspase-1/ICE is a key step in the inflammatory response. IL-1 beta binds to IL-1 RI and IL-1 RII. The IL-1 receptor accessory protein (IL-1 RAcP) associates with IL-1 RI and is required for IL-1 RI signal transduction, and IL-1ra is a secreted molecule that functions as a competitive inhibitor of IL-1 bioactivity.

Showing 1-26 out of 26 IL-1 beta/IL-1F2 Products

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Recombinant Human IL-1 beta/IL-1F2 Protein

 201-LB282  
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Recombinant Human IL-1 beta/IL-1F2 Protein, CF

 201-LB/CF282  
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Recombinant Mouse IL-1 beta/IL-1F2 Protein

 401-ML103  
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Recombinant Mouse IL-1 beta/IL-1F2 Protein, CF

 401-ML/CF103  
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Recombinant Rat IL-1 beta/IL-1F2 Protein

 501-RL35  
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Recombinant Rat IL-1 beta/IL-1F2 Protein, CF

 501-RL/CF35  
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Recombinant Porcine IL-1 beta/IL-1F2 Protein

 681-PI5  
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Recombinant Porcine IL-1 beta/IL-1F2 Protein, CF

 681-PI/CF5  
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Recombinant Human IL-1 beta/IL-1F2 GMP Protein, CF


Animal-Free
 201-GMP 
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Recombinant Equine IL-1 beta/IL-1F2 Protein

 3340-EL1  
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Recombinant Equine IL-1 beta/IL-1F2 Protein, CF

 3340-EL/CF1  
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Recombinant Rhesus Macaque IL-1 beta/IL-1F2 Protein

 1318-RL1  
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Recombinant Rhesus Macaque IL-1 beta/IL-1F2 Protein, CF

 1318-RL/CF1  
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ProDots Recombinant Human IL-1 beta/IL-1F2 Protein


Supplied as ready-to-use 5 ug protein balls
 PRD201 
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Recombinant Rabbit IL-1 beta/IL-1F2 Protein

 7464-RB1  
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Recombinant Rabbit IL-1 beta/IL-1F2 Protein, CF

 7464-RB/CF1  
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Recombinant Human IL-1 beta/IL-1F2, Animal-Free Protein

 AFL2011  
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Recombinant Cotton Rat IL-1 beta/IL-1F2 Protein

 1009-CL 
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Recombinant Cotton Rat IL-1 beta/IL-1F2 Protein, CF

 1009-CL/CF 
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Recombinant Feline IL-1 beta/IL-1F2 Protein

 1796-FL 
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Recombinant Feline IL-1 beta/IL-1F2 Protein, CF

 1796-FL/CF 
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Recombinant Canine IL-1 beta/IL-1F2 Protein

 3747-CL 
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Recombinant Canine IL-1 beta/IL-1F2 Protein, CF

 3747-CL/CF 
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Recombinant Guinea Pig IL-1 beta/IL-1F2 Protein

 6226-GL 
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Recombinant Guinea Pig IL-1 beta/IL-1F2 Protein, CF

 6226-GL/CF 
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Recombinant Mouse IL-1 beta/IL-1F2, Animal-Free Protein

 AFL401 
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