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IL-1 beta/IL-1F2: Products

IL-1 beta (Interleukin-1 beta) is produced in response to inflammatory agents, infections, or microbial endotoxins. It plays a central role in immune and inflammatory responses, bone remodeling, fever, carbohydrate metabolism, and GH/IGF-I physiology. IL-1 beta dysregulation is implicated in many pathological conditions including sepsis, rheumatoid arthritis, inflammatory bowel disease, acute and chronic myelogenous leukemia, insulin-dependent diabetes mellitus, atherosclerosis, neuronal injury, and aging-related diseases. Intracellular cleavage of the IL-1 beta precursor by Caspase-1/ICE is a key step in the inflammatory response. IL-1 beta binds to IL-1 RI and IL-1 RII. The IL-1 receptor accessory protein (IL-1 RAcP) associates with IL-1 RI and is required for IL-1 RI signal transduction, and IL-1ra is a secreted molecule that functions as a competitive inhibitor of IL-1 bioactivity.

Showing 1-8 out of 8 IL-1 beta/IL-1F2 Products

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Contains 4 membranes - each spotted in duplicate with 40 different cytokine antibodies
ARY00689  
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Contains 4 membranes - each spotted in duplicate with 36 different cytokine antibodies
ARY005B79  
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Contains 4 membranes - each spotted in duplicate with 55 different cytokine antibodies
ARY00741  
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Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies
ARY022B1  
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Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies
ARY028 
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Contains 4 membranes - each spotted in duplicate with 29 different cytokine antibodies
ARY0088  
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Contains 4 membranes-each spotted in duplicate with 58 different obesity-related antibodies
ARY024 
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Contains 4 membranes - each spotted in duplicate with 30 different obesity-related antibodies
ARY016 
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