IL-12/IL-23 p40: Products

IL-12 (Interleukin-12) is a secreted heterodimeric cytokine that contains disulfide-linked p35 and p40 subunits. The p40 subunit is also a subunit of the heterodimeric IL-23. IL-12 is produced by macrophages, dendritic cells, monocytes, Langerhans cells, neutrophils, keratinocytes, microglia, and non-germinal center B cells. It acts  through a receptor complex that contains the ligand binding IL-12 R alpha 1 and the signal transducing IL-12 R alpha 2. IL-12 can enhance cytotoxic activity and induce Interferon-gamma production in NK cells, T cells and dendritic epidermal T cells. In conjunction with IL-23 and IL-27, IL-12 promotes the development of a Th1 immune response.

Showing 1-7 out of 7 IL-12/IL-23 p40 Products

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Recombinant Human IL-12/IL-23 p40 Monomer Protein

 309-IL4  
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Recombinant Mouse IL-12/IL-23 p40 Homodimer Protein

 499-ML8  
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Recombinant Mouse IL-12/IL-23 p40 Homodimer Protein, CF

 499-ML/CF8  
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Recombinant Canine IL-12/IL-23 p40 Protein

 1969-CL 
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Recombinant Canine IL-12/IL-23 p40 Protein, CF

 1969-CL/CF 
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Recombinant Feline IL-12/IL-23 p40 Protein

 2117-FL 
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Recombinant Feline IL-12/IL-23 p40 Protein, CF

 2117-FL/CF 
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