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IL-17C: Products

Interleukin‑17C is a 15‑20 kDa disulfide-linked dimeric cytokine that plays an important role in mucosal immunity and chronic inflammation. IL‑17C binds to IL‑17 RE with high affinity and to IL‑17 RA with low affinity. These two receptor chains can associate into a heterodimeric receptor for IL‑17C. IL‑17C expression is induced by inflammatory stimulation in colon and airway epithelial cells, keratinocytes, CD4+ T cells, macrophages, and dendritic cells. It is upregulated in various chronic inflammatory diseases including psoriasis, cystic fibrosis, and chronic obstructive pulmonary disease (COPD). The interaction of IL‑17C with IL‑17 RE promotes mucosal immunity through the induction of anti‑bacterial peptides and pro‑inflammatory cytokines and chemokines. IL‑17C action supports the integrity of the colon epithelium following infection induced damage but also contributes to psoriatic skin thickening and the progression of arthritis.

 

Showing 1-28 out of 28 IL-17C Products

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Human Magnetic Luminex Assay

LXSAHM60  
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Build your own with our Luminex Assay Customization Tool.

Human IL-17C Antibody

CyTOF-ready, ELISA(Cap), Flow, IHC, WBMAB12341  
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Recombinant Human IL-17C Protein

Binding Activity1234-IL2  
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Recombinant Human IL-17C Protein, CF

Binding Activity1234-IL/CF2  
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Human IL-17C DuoSet ELISA

ELISADY12344  
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Mouse IL-17C Antibody

WBAF23061  
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Human IL-17C Biotinylated Antibody

ELISA(Det), WBBAF1234 
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Mouse IL-17C Antibody

CyTOF-ready, FlowMAB23061 
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Recombinant Mouse IL-17C Protein

Binding Activity2306-ML 
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Recombinant Mouse IL-17C Protein, CF

Binding Activity2306-ML/CF 
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Recombinant Human IL-17C (CHO-expressed) Protein

Bioactivity9640-IL 
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Recombinant Human IL-17C (CHO-expressed) Protein, CF

Bioactivity9640-IL/CF 
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Mouse IL-17C Antibody

WBMAB2306 
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Human IL-17C Antibody

WBAF1234 
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Human IL-17C Alexa Fluor® 488-conjugated Antibody

FlowIC1234G 
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Human IL-17C Alexa Fluor® 700-conjugated Antibody

FlowIC1234N 
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Human IL-17C Alexa Fluor® 647-conjugated Antibody

FlowIC1234R 
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Human IL-17C Alexa Fluor® 750-conjugated Antibody

FlowIC1234S 
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Human IL-17C Alexa Fluor® 594-conjugated Antibody

FlowIC1234T 
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Human IL-17C Alexa Fluor® 350-conjugated Antibody

FlowIC1234U 
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Human IL-17C Alexa Fluor® 405-conjugated Antibody

FlowIC1234V 
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Mouse IL-17C Alexa Fluor® 488-conjugated Antibody

FlowIC23061G 
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Mouse IL-17C Alexa Fluor® 700-conjugated Antibody

FlowIC23061N 
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Mouse IL-17C Alexa Fluor® 647-conjugated Antibody

FlowIC23061R 
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Mouse IL-17C Alexa Fluor® 750-conjugated Antibody

FlowIC23061S 
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Mouse IL-17C Alexa Fluor® 594-conjugated Antibody

FlowIC23061T 
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Mouse IL-17C Alexa Fluor® 350-conjugated Antibody

FlowIC23061U 
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Mouse IL-17C Alexa Fluor® 405-conjugated Antibody

FlowIC23061V 
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