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IL-18/IL-1F4: Products

IL-18 (Interleukin-18) is secreted by macrophages, dendritic cells, and epithelial cells. Circulating mature IL-18 is sequestered by soluble IL-18 binding proteins (IL-18 BP) that inhibit IL-18 bioactivity. IL-18 signals through a receptor complex that contains IL-18 R alpha IL-18 R beta. It synergizes with other cytokines to activate NK, Th1, and Th17 cells and to increase the production of IFN-gamma. It can also promote Th2 cytokine release which reduces the effectiveness of antiviral responses. Increased levels of active IL-18 contribute to the severity of autoimmunity and hypertension, while deficiency of IL-18 results in symptoms of metabolic syndrome. In cancer, IL-18 stimulates Th1 and NK cells to target tumor cells, but it can also promote angiogenesis, metastasis, and tumor cell immune evasion.

Showing 1-50 out of 69 IL-18/IL-1F4 Products

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Human Magnetic Luminex Assay

LXSAHM59  
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Human Total IL-18/IL-1F4 Quantikine ELISA Kit

ELISADL180 
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Human IL-18/IL-1F4 ELISA


Human IL-18/IL-1F4 Quantikine ELISA Kit is now available, catalog # DL180.
ELISA762038  
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Human IL-18/IL-1F4 Antibody

B/N, ELISA(Cap), IPD044-318  
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Mouse IL-18/IL-1F4 ELISA

ELISA762530  
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Recombinant Human IL-18/IL-1F4 Protein

Bioactivity9124-IL4  
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Recombinant Human IL-18/IL-1F4 Protein, CF

Bioactivity9124-IL/CF4  
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Recombinant Human IL-18/IL-1F4 Protein


A New rhIL-18 is Now Available! Competitively priced; Higher purity; Lower endotoxin; Manufactured in-house!
New Product 9124-IL
BioactivityB001-530  
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Recombinant Mouse IL-18/IL-1F4 Protein

Bioactivity9139-IL 
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Recombinant Mouse IL-18/IL-1F4 Protein


A New rmIL-18 is Now Available! Competitively priced; Enhanced stability; Lower endotoxin specifications; Made in-house!
New Product 9139-IL
 B002-527  
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Human IL-18/IL-1F4 Antibody

IPD045-31  
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Human Total IL-18 DuoSet ELISA

ELISADY318-053  
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Human Luminex Assay

LXSAH6  
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Recombinant Mouse IL-18/IL-1F4 Protein, CF

Bioactivity9139-IL/CF 
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Rat Magnetic Luminex Assay

LXSARM2  
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Proteome Profiler Human Cytokine Array Kit


Contains 4 membranes - each spotted in duplicate with 36 different cytokine antibodies
ARY005B133  
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Human IL-18/IL-1F4 Biotinylated Antibody

D045-69  
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Rat IL-18/IL-1F4 Antibody

B/N, WBAF5215  
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Recombinant Rat IL-18/IL-1F4 Protein

Bioactivity521-RL8  
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Recombinant Rat IL-18/IL-1F4 Protein, CF

Bioactivity521-RL/CF8  
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Mouse IL-18/IL-1F4 Antibody

ELISA(Cap), IPD047-34  
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Mouse IL-18/IL-1F4 Biotinylated Antibody

D048-63  
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Human IL-18/IL-1F4 Propeptide Antibody

CyTOF-ready, Flow, WBMAB6463  
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Recombinant Porcine IL-18/IL-1F4 Protein

Bioactivity588-PL4  
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Recombinant Porcine IL-18/IL-1F4 Protein, CF

Bioactivity588-PL/CF4  
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Mouse IL-18/IL-1F4 Antibody

B/N, IPD048-35  
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Human IL-18/IL-1F4 Propeptide PE-conjugated Antibody

FlowIC646P3  
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Human/Rhesus Macaque IL-18/IL-1F4 Antibody

B/N, ELISA, ICC/IF, KO, WBAF2548 
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Human IL-18/IL-1F4 Antibody

WBD043-34  
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Mouse IL-18/IL-1F4 Antibody

WBD046-31  
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Recombinant Human IL-18/IL-1F4 Protein, CF


A New rhIL-18 is Available! Competitively priced; Higher purity; Lower endotoxin specs; Made in-house!
New Product 9124-IL/CF
BioactivityB003-22  
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Recombinant Mouse IL-18/IL-1F4 Protein, CF


A New rmIL-18 is Now Available! Competitively priced; Enhanced stability; Lower endotoxin spec; Made in-house!
New Product 9139-IL/CF
BioactivityB004-53  
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Rat IL-18/IL-1F4 Antibody

WBMAB5214  
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Recombinant Human IL-18/IL-1F4 Protein, CF


A New rhIL-18 is Available! Competitively priced; Higher purity; Lower endotoxin specs; Made in-house!
New Product 9124-IL/CF
BioactivityB003-52  
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Recombinant Mouse IL-18/IL-1F4 Protein, CF


A New rmIL-18 is Now Available! Competitively priced; Enhanced stability; Lower endotoxin spec; Made in-house!
New Product 9139-IL/CF
BioactivityB004-23  
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Human IL-18/IL-1F4 Propeptide Antibody

WBAF6463  
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Human IL-18/IL-1F4 Antibody

CyTOF-ready, ELISA, Flow, ICC/IFMAB2548 
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Rat IL-18/IL-1F4 Biotinylated Antibody

WBBAF5212  
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Porcine IL-18/IL-1F4 Biotinylated Antibody

WBBAF588 
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Human IL-18/IL-18 BPa Complex DuoSet ELISA

ELISADY8936-05 
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Canine IL-18/IL-1F4 Antibody

ICC/IF, WBAF2924 
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Porcine IL-18/IL-1F4 Antibody

ICC/IF, WBAF588 
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Feline IL-18/IL-1F4 Antibody

B/N, WBAF5989 
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Canine IL-18/IL-1F4 Antibody

ICC/IF, WBMAB29241 
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Human IL-18/IL-1F4 Antibody


Recombinant Monoclonal Antibody.
B/NMAB9124 
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Recombinant Rhesus Macaque IL-18/IL-1F4 Protein

Bioactivity2548-RM 
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Recombinant Rhesus Macaque IL-18/IL-1F4 Protein, CF

Bioactivity2548-RM/CF 
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Human IL-18/IL-1F4 Propeptide Alexa Fluor® 488-conjugated Antibody

FlowIC646G 
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Canine IL-18/IL-1F4 Antibody

WBMAB2924 
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Human IL-18/IL-1F4 Antibody

B/NMAB91241 
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