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IL-21: Products

IL-21 (Interleukin-21) is member of the family of cytokines that utilize the common gamma chain as a receptor subunit. This subunit is also a component of the receptors for IL-2, IL-4, IL-7, IL-9, and IL-15. IL-21 is produced by activated T follicular helper cells (Tfh), Th17 cells, and NKT cells. It exerts its biological effects through a heterodimeric receptor complex of the common gamma chain and the IL-21-specific IL-21 R. IL-21 supports Tfh cell development, immunoglobulin affinity maturation, plasma cell differentiation, B cell memory responses, and the migration of dendritic cells to draining lymph nodes. It costimulates the activation, proliferation, and survival of CD8+ T cells and NKT cells and promotes Th17 cell polarization. It blocks the generation of regulatory T cells and their suppressive effects on CD4+ T cells. In addition, IL-21 suppresses cutaneous hypersensitivity reactions by limiting allergen-specific IgE production and mast cell degranulation.

Showing 1-26 out of 26 IL-21 Products

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DescriptionApplicationCat#CitationsImages 

Human Magnetic Luminex Assay

LXSAHM18  
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Build your own with our Luminex Assay Customization Tool.

Recombinant Mouse IL-21 Protein

 594-ML30  
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Recombinant Mouse IL-21 Protein, CF

 594-ML/CF30  
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Human Luminex Assay

LXSAH5  
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Build your own with our Luminex Assay Customization Tool.

Mouse IL-21 DuoSet ELISA

ELISADY59421  
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Recombinant Human IL-21 Protein

 8879-IL4  
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Recombinant Human IL-21 Protein, CF

 8879-IL/CF4  
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Mouse IL-21 Antibody

B/N, ELISA(Cap), ICC/IF, WBAF59410  
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Mouse IL-21 Biotinylated Antibody

ELISA(Det), WBBAF5945  
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Proteome Profiler Human Cytokine Array Kit


Contains 4 membranes - each spotted in duplicate with 36 different cytokine antibodies
ARY005B108  
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Mouse IL-21 Antibody

CyTOF-ready, Flow, WBMAB5941  
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Mouse IL-21 PE-conjugated Antibody

FlowIC594P2  
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Mouse IL-21 APC-conjugated Antibody

FlowIC594A1  
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Canine IL-21 Antibody

B/NAF5849 
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Mouse IL-21 PerCP-conjugated Antibody

FlowIC594C 
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Mouse IL-21 Alexa Fluor® 488-conjugated Antibody

FlowIC594G 
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Recombinant Canine IL-21 Protein

 5849-ML 
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Recombinant Canine IL-21 Protein, CF

 5849-ML/CF 
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Recombinant Rabbit IL-21 Protein

 7274-RB 
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Recombinant Rabbit IL-21 Protein, CF

 7274-RB/CF 
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Mouse IL-21 Alexa Fluor® 700-conjugated Antibody

FlowIC594N 
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Mouse IL-21 Alexa Fluor® 647-conjugated Antibody

FlowIC594R 
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Mouse IL-21 Alexa Fluor® 750-conjugated Antibody

FlowIC594S 
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Mouse IL-21 Alexa Fluor® 594-conjugated Antibody

FlowIC594T 
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Mouse IL-21 Alexa Fluor® 350-conjugated Antibody

FlowIC594U 
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Mouse IL-21 Alexa Fluor® 405-conjugated Antibody

FlowIC594V 
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