IkB Kinase Inhibitors: Products

The classical active IKK complex, composed of IKK alpha, IKK beta, and two forms of processed IKK gamma, phosphorylates and inactivates IkB, resulting in the release and nuclear translocation of active NFkB. The regulatory IKK gamma is required for activation of the IKK complex. IKK epsilon is an IKK-related kinase with 30% structural homology to IKK alpha and beta, and is present in a subset of IKK complexes.

Showing 1-12 out of 12 IkB Kinase Inhibitors Products

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TPCA-1


Potent, selective inhibitor of IKKβ
25597  
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ACHP


Selective IKKα and IKKβ inhibitor
45472  
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IKK 16


Selective inhibitor of IKK
25393  
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IMD 0354


Inhibitor of IKKβ
26113  
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BMS 345541


Selective allosteric inhibitor of IKK; anti-inflammatory
4806 
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Amlexanox


Inhibitor of TBK1 and IKKε; antiallergic agent
48571  
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SC 514


IKKβ inhibitor; attenuates NF-κB-induced gene expression
33181  
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PF 184


Potent and selective IKKβ inhibitor
42381  
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PS 1145 dihydrochloride


Selective IKK inhibitor; orally active
4569 
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ML 120B dihydrochloride


Novel IKK2-selective inhibitor
4899 
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BI 605906


Selective IKKβ inhibitor
5300 
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GSK 319347A


Potent and selective IKKε inhibitor
5672 
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